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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Id | http://purl.obolibrary.org/obo/CHEBI_5164
http://purl.obolibrary.org/obo/CHEBI_5164
|
|---|---|
| Preferred Name | fosinopril sodium |
| Definitions |
The sodium salt of fosinopril. It is used for the treatment of hypertension and heart failure. A pro-drug, its phosphinate ester group is hydrolysed in vivo to give the corresponding phosphininc acid, fosinoprilat, which is the active metabolite.
|
| Synonyms |
sodium (2S,4S)-4-cyclohexyl-1-({[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylate
fosinopril sodium
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The sodium salt of fosinopril. It is used for the treatment of hypertension and heart failure. A pro-drug, its phosphinate ester group is hydrolysed in vivo to give the corresponding phosphininc acid, fosinoprilat, which is the active metabolite. |
|---|---|
| label |
fosinopril sodium
|
| prefLabel |
fosinopril sodium
|
| database_cross_reference |
PMID:9604795
Patent:WO02088149
CAS:88889-14-9
Beilstein:6840563
PMID:18154978
Patent:US2006160772
PMID:2967089
KEGG:D00622
See more
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|
| notation |
CHEBI:5164
|
| in_subset | |
| inchi |
InChI=1S/C30H46NO7P.Na/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24;/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35);/q;+1/p-1/t25-,26+,30?,39?;/m1./s1
|
| id |
CHEBI:5164
|
| has part | |
| charge |
0
|
| has_obo_namespace |
chebi_ontology
|
| formula |
C30H45NNaO7P
|
| subClassOf | |
| overlaps | |
| inchikey |
TVTJZMHAIQQZTL-HREVRLCXSA-M
|
| mass |
585.64430
|
| monoisotopicmass |
585.28313
|
| type | |
| smiles |
[Na+].[H][C@]1(C[C@H](N(C1)C(=O)CP(=O)(CCCCc1ccccc1)OC(OC(=O)CC)C(C)C)C([O-])=O)C1CCCCC1
|
| RO_0000087 | |
| has_exact_synonym |
sodium (2S,4S)-4-cyclohexyl-1-({[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylate
fosinopril sodium
|
| bearer of | |
| alternative term |
sodium (2S,4S)-4-cyclohexyl-1-({[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylate
fosinopril sodium
|
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