BioAssay Ontology

Last uploaded: February 21, 2024
Preferred Name

liver

Synonyms

jecur

iecur

Definitions

An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO].

ID

http://purl.obolibrary.org/obo/UBERON_0002107

axiom_lost_from_external_ontology

relationship type change: differentiates_from endoderm (AAO:0000139) CHANGED TO: develops_from endoderm (UBERON:0000925)[AAO]

database_cross_reference

http://www.snomedbrowser.com/Codes/Details/181268008

http://linkedlifedata.com/resource/umls/id/C0023884

http://en.wikipedia.org/wiki/Liver

VHOG:0000257

MIAA:0000097

GAID:288

EFO:0000887

BTO:0000759

MESH:D008099

OpenCyc:Mx4rvVimppwpEbGdrcN5Y29ycA

galen:Liver

EV:0100089

FMA:7197

MA:0000358

NCIT:C12392

ZFA:0000123

TAO:0000123

UMLS:C0023884

XAO:0000133

EHDAA:2197

EHDAA2:0000997

EMAPA:16846

MAT:0000097

AAO:0010111

CALOHA:TS-0564

depicted by

http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Leber_Schaf.jpg/200px-Leber_Schaf.jpg

http://upload.wikimedia.org/wikipedia/commons/6/64/Leber_Schaf.jpg

Leber:Schaf.jpg

external_definition

Organ which secretes bile and participates in formation of certain blood proteins.[AAO]

external_ontology_notes

Only ZFA considers this part_of immune system - we weaken this to an overlaps relation, as in general it's only a subset of cells that have clear immune function.

function_notes

secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO].

has_obo_namespace

uberon

has_related_synonym

jecur

iecur

has_relational_adjective

hepatic

homologous_in

http://purl.obolibrary.org/obo/NCBITaxon_7742

homology_notes

All vertebrates possess a liver (reference 1); Later in craniate evolution, an anterior gill arch was transformed into jaws, and many new types of feeding subsequently evolved.(...) A liver evolved that, among its many functions, stores considerable energy as glycogen or lipid (reference 2).[well established][VHOG]

id

UBERON:0002107

imported from

http://purl.obolibrary.org/obo/uberon.owl

in_subset

http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#organ_slim

http://purl.obolibrary.org/obo/uberon/core#efo_slim

http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim

http://purl.obolibrary.org/obo/uberon/core#organ_slim

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

http://purl.obolibrary.org/obo/uberon/core#major_organ

http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim

http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim

http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core

http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#major_organ

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

liver

notation

UBERON:0002107

prefLabel

liver

taxon_notes

An organ sometimes referred to as a liver is found associated with the digestive tract of the primitive chordate Amphioxus. However, this is an enzyme secreting gland, not a metabolic organ, and it is unclear how truly homologous it is to the vertebrate liver. The zebrafish liver differs from the mammalian liver in that the hepatocytes are not clearly organized in cords or lobules and the typical portal triads are not apparent. In addition, the zebrafish liver does not have Kuppfer cells. Furthermore, a clear distinction can be made between the male and female liver in the adult zebrafish. The female hepatocytes are very basophilic (Figure 15c) as a result of the production of vitellogenin (Van der Ven et al. 2003).

The liver is found in all vertebrates, and is typically the largest visceral organ. Its form varies considerably in different species, and is largely determined by the shape and arrangement of the surrounding organs. Nonetheless, in most species it is divided into right and left lobes; exceptions to this general rule include snakes, where the shape of the body necessitates a simple cigar-like form. The internal structure of the liver is broadly similar in all vertebrates.

textual definition

An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO].

subClassOf

http://purl.obolibrary.org/obo/UBERON_0001062

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/UBERON_0002107 UBERON SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 OBA SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 FOODON SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 FOODON SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 NPOKB SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 CL SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 EFO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 OAE SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 RBO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 PDRO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 EUPATH SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 CLO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 OBI SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 INBANCIDO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 FOVT SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 OCMR SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 ONE SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 HOIP SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 DTO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 OBI_BCGO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 DOID SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 XPO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 ORCS SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 EGO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 SP SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 HSO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 COVID-19 SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 PCL SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 PATO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 NIFDYS SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 OBIB SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 BERO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 NBO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 HHEAR SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 TXPO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 OBA SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 ODAE SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 ICDO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 CIDO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 UPHENO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 OBI_IEE SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 OCVDAE SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 KTAO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 OPL SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 MAXO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 CCF SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 FNS-H SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 AISM SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 NMDCO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002107 UBERON LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 OBA LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 FOODON LOOM
http://purl.bioontology.org/ontology/CMDO/CM0546 CMDO LOOM
http://purl.obolibrary.org/obo/EHDA_6983 EHDA LOOM
http://vavlab.ee.boun.edu.tr/carera/onlira.owl#Liver ONLIRA LOOM
http://vavlab.ee.boun.edu.tr/carera/onlira.owl#Liver LICO LOOM
http://purl.obolibrary.org/obo/VHOG_0000257 VHOG LOOM
http://www.semanticweb.org/ontologies/2010/5/22/Ontology1277229984000.owl#HPI:0000040 HPIO LOOM
http://purl.obolibrary.org/obo/EHDA_4935 EHDA LOOM
http://purl.obolibrary.org/obo/MFO_0003060 MFO LOOM
http://purl.obolibrary.org/obo/XAO_0000133 XPO LOOM
http://purl.obolibrary.org/obo/XAO_0000133 UPHENO LOOM
http://purl.obolibrary.org/obo/XAO_0000133 XAO LOOM
urn:absolute:RadiationOncologyStructuresOntology#Liver ROS LOOM
http://purl.bioontology.org/ontology/LNC/MTHU002039 LOINC LOOM
http://purl.bioontology.org/ontology/CSP/1754-0095 CRISP LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12392 NCIT LOOM
http://www.semanticweb.org/ontologies/2012/11/abnormalities.owl#phenodb:1110 IFAR LOOM
http://localhost/plosthes.2017-1#9749 PLOSTHES LOOM
http://www.projecthalo.com/aura#Liver AURA LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Liver APAONTO LOOM
http://purl.obolibrary.org/obo/EHDA_2198 EHDA LOOM
http://purl.jp/bio/11/meo/MEO_0000483 MEO LOOM
http://www.semanticweb.org/hanfei/ontologies/2020/9/untitled-ontology-1306#Liver COVID-19-ONT-PM LOOM
http://doe-generated-ontology.com/OntoPneumo#Foie ONTOPNEUMO LOOM
http://scai.fraunhofer.de/CSEO#Liver CSEO LOOM
http://purl.obolibrary.org/obo/NCIT_C12392 BERO LOOM
http://www.limics.fr/ontologies/ontoparonmed#Foie ONTOPARON LOOM
http://sig.uw.edu/fma#Liver HUPSON LOOM
http://purl.obolibrary.org/obo/EHDAA_2197 EHDAA LOOM
http://purl.bioontology.org/ontology/MESH/D008099 MESH LOOM
http://id.nlm.nih.gov/mesh/D008099 MDM LOOM
http://purl.bioontology.org/ontology/VANDF/4017451 VANDF LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Liver STMSO LOOM
http://purl.obolibrary.org/obo/MA_0000358 MA LOOM
http://radlex.org/RID/RID58 RADLEX LOOM
http://purl.obolibrary.org/obo/EHDA_10426 EHDA LOOM
http://purl.obolibrary.org/obo/MAT_0000097 MAT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008099 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Liver GALEN LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU000220 OMIM LOOM
http://purl.obolibrary.org/obo/ZFA_0000123 ZFA LOOM
http://purl.obolibrary.org/obo/ZFA_0000123 UPHENO LOOM
http://purl.obolibrary.org/obo/ZFA_0000123 ZP LOOM
http://purl.bioontology.org/ontology/LNC/LP191611-5 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/LA4584-4 LOINC LOOM
http://purl.obolibrary.org/obo/EHDA_3055 EHDA LOOM
http://purl.obolibrary.org/obo/EMAPA_16846 EMAPA LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0023884 OCHV LOOM
http://purl.obolibrary.org/obo/BTO_0000759 ENM LOOM
http://purl.obolibrary.org/obo/BTO_0000759 DTO LOOM
http://purl.obolibrary.org/obo/BTO_0000759 BTO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU065906 LOINC LOOM
http://purl.org/obo/owlapi/fma#FMA_7197 BIOMODELS LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Liver SYN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7494 OCHV LOOM
http://purl.obolibrary.org/obo/EHDA_8070 EHDA LOOM
http://purl.obolibrary.org/obo/EHDA_5894 EHDA LOOM
http://bioportal.bioontology.org/ontologies/FISHO#FISHO_0000303 FISHO LOOM
http://www.ifomis.org/acgt/1.0#Liver ACGT-MO LOOM
http://purl.bioontology.org/ontology/LNC/LP29289-3 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/LP199933-5 LOINC LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 FOODON LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 NPOKB LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 CL LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 EFO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 OAE LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 RBO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 PDRO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 EUPATH LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 CLO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 OBI LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 INBANCIDO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 FOVT LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 OCMR LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 ONE LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 HOIP LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 DTO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 OBI_BCGO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 DOID LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 XPO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 ORCS LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 EGO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 SP LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 HSO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 COVID-19 LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 PCL LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 PATO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 NIFDYS LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 OBIB LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 NBO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 HHEAR LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 TXPO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 OBA LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 ODAE LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 ICDO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 CIDO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 UPHENO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 OBI_IEE LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 OCVDAE LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 NIFSTD LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 KTAO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 GENEPIO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 OPL LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 MAXO LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 CCF LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 GO-PLUS LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 FNS-H LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 AISM LOOM
http://purl.obolibrary.org/obo/UBERON_0002107 NMDCO LOOM
http://purl.obolibrary.org/obo/EHDA_3994 EHDA LOOM
http://purl.org/sig/fma/Liver ONSTR LOOM
http://www.semanticweb.org/admin/ontologies/2023/4/OMDO#Liver OMDO LOOM
http://purl.org/sig/ont/fma/fma7197 FMA LOOM
http://purl.org/sig/ont/fma/fma7197 ROO LOOM
http://purl.obolibrary.org/obo/TAO_0000123 TAO LOOM
http://purl.obolibrary.org/obo/OMIT_0009182 OMIT LOOM
http://purl.bioontology.org/ontology/LNC/LP7400-7 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#A03.620 RH-MESH LOOM
http://www.semanticweb.org/ontologies/2010/10/BPO.owl#liver BHO LOOM
http://purl.jp/bio/4/id/200906045182197076 IOBC LOOM
http://purl.obolibrary.org/obo/EHDA_9312 EHDA LOOM
http://www.semanticweb.org/ontologies/epo.owl#OPPIO_a000385 EPO LOOM
http://purl.obolibrary.org/obo/EHDAA2_0000997 EHDAA2 LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000145839 NDFRT LOOM
http://purl.bioontology.org/ontology/RCD/7N330 RCD LOOM
http://www.semanticweb.org/david/ontologies/2013/0/pathLex.owl#1.3.6.1.4.1.19376.1.8.2.1.881 PATHLEX LOOM

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