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G Protein-Coupled Receptor BioAssays Ontology
Last uploaded:
October 28, 2013
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| Preferred Name | Guanine nucleotide exchange factor | |
| Synonyms |
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| ID |
http://www.bioassayontology.org/bao#BAO_0200497 |
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| description |
RhoGEFs, Synembryns
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| definition |
Guanine nucleotide exchange factors (GEFs) activate monomeric GTPases by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP). A variety of unrelated structural domains have been shown to exhibit guanine nucleotide exchange activity. Some GEFs can activate multiple GTPases while others are specific to a single GTPase.
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| label |
Guanine nucleotide exchange factor
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| prefixIRI |
BAO_0200497
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| prefLabel |
Guanine nucleotide exchange factor
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| subClassOf |
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