Preferred Name |
aztreonam |
|
Synonyms |
ATM Primbactam |
|
Definitions |
Aztreonam was the first monobactam discovered, and is greatly effective against Gram-negative bacteria while inactive against Gram-positive bacteria. Artreonam is a poor substrate for beta-lactamases, and may even act as an inhibitor. In Gram-negative bacteria, Aztreonam interferes with filamentation, inhibiting cell division and leading to cell death. |
|
ID |
http://purl.obolibrary.org/obo/ARO_3000550 |
|
database_cross_reference |
pubchem.compound:5742832 |
|
definition |
Aztreonam was the first monobactam discovered, and is greatly effective against Gram-negative bacteria while inactive against Gram-positive bacteria. Artreonam is a poor substrate for beta-lactamases, and may even act as an inhibitor. In Gram-negative bacteria, Aztreonam interferes with filamentation, inhibiting cell division and leading to cell death. |
|
has_exact_synonym |
ATM Primbactam |
|
has_obo_namespace |
antibiotic_resistance |
|
id |
ARO:3000550 |
|
label |
aztreonam |
|
notation |
ARO:3000550 |
|
prefLabel |
aztreonam |
|
subClassOf |