Preferred Name |
isoniazid |
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Synonyms |
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Definitions |
Isoniazid is an organic compound that is the first-line anti tuberculosis medication in prevention and treatment. As a prodrug, it is activated by mycobacterial catalase-peroxidases such as M. tuberculosis KatG. Isoniazid inhibits mycolic acid synthesis, which prevents cell wall synthesis in mycobacteria. |
|
ID |
http://purl.obolibrary.org/obo/ARO_3000520 |
|
database_cross_reference |
pubchem.compound:3767 |
|
definition |
Isoniazid is an organic compound that is the first-line anti tuberculosis medication in prevention and treatment. As a prodrug, it is activated by mycobacterial catalase-peroxidases such as M. tuberculosis KatG. Isoniazid inhibits mycolic acid synthesis, which prevents cell wall synthesis in mycobacteria. |
|
has_obo_namespace |
antibiotic_resistance |
|
id |
ARO:3000520 |
|
label |
isoniazid |
|
notation |
ARO:3000520 |
|
prefLabel |
isoniazid |
|
subClassOf |
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