Antibiotic Resistance Ontology

Last uploaded: August 28, 2024
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Preferred Name

glycopeptide antibiotic
Synonyms
Definitions

Glycopeptide antibiotics are natural products produced non-ribosomally by Actinomycetales bacteria. With the exception of bleomycins, they act by binding the terminal D-Ala-D-Ala in peptidoglycan precursors of the growing bacterial cell wall and are generally active against Gram-positive bacteria. This inhibits transglycosylation leading to cell death due to osmotic stress.
ID

http://purl.obolibrary.org/obo/ARO_3000081
definition

Glycopeptide antibiotics are natural products produced non-ribosomally by Actinomycetales bacteria. With the exception of bleomycins, they act by binding the terminal D-Ala-D-Ala in peptidoglycan precursors of the growing bacterial cell wall and are generally active against Gram-positive bacteria. This inhibits transglycosylation leading to cell death due to osmotic stress.
has_obo_namespace

antibiotic_resistance
id

ARO:3000081
label

glycopeptide antibiotic
notation

ARO:3000081
prefLabel

glycopeptide antibiotic
subClassOf

http://purl.obolibrary.org/obo/ARO_1000003
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