Ascomycete Phenotype Ontology

Last uploaded: October 23, 2024
Preferred Name

necrotic cell death
Synonyms
Definitions

A form of cell death that is distinct from apoptosis. Cells undergoing necrotic cell death undergo overall destruction. They can be distinguished from apoptotic cells because they lose membrane integrity, which only happens late in apoptosis (positive propidium iodide staining), and do not externalize phosphatidylserine (measured by annexin V staining) as do apoptotic cells.

ID

http://purl.obolibrary.org/obo/APO_0000220

definition

A form of cell death that is distinct from apoptosis. Cells undergoing necrotic cell death undergo overall destruction. They can be distinguished from apoptotic cells because they lose membrane integrity, which only happens late in apoptosis (positive propidium iodide staining), and do not externalize phosphatidylserine (measured by annexin V staining) as do apoptotic cells.

has_alternative_id

YPO:0000220

has_obo_namespace

observable

id

APO:0000220

in_subset

http://purl.obolibrary.org/obo/apo#SGD

http://purl.obolibrary.org/obo/apo#CGD

http://purl.obolibrary.org/obo/apo#AspGD

http://purl.obolibrary.org/obo/apo#CryptoGD

label

necrotic cell death

notation

APO:0000220

prefLabel

necrotic cell death

treeView

http://purl.obolibrary.org/obo/APO_0000312

subClassOf

http://purl.obolibrary.org/obo/APO_0000312

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