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| ID: | PRO:000000001 |
| Full Id: | PRO:000000001 |
| Definitions: | A biological macromolecule that is composed of amino acids linked in a linear sequence (a polypeptide chain) and is genetically encoded. Proteins descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic. |
| Sub Class: | dual specificity mitogen-activated protein kinase kinase 6 proto-oncogene SRC-like tyrosine-protein kinase tumor necrosis factor receptor superfamily member 1B syntaxin binding protein tumor necrosis factor receptor superfamily member 1A tumor necrosis factor receptor superfamily member 13C tumor necrosis factor receptor superfamily member 13B tumor necrosis factor receptor superfamily member 12A tumor necrosis factor receptor superfamily member 11A NRAMP-like divalent ion transporter tumor necrosis factor receptor superfamily member 10D tumor necrosis factor receptor superfamily member 10C serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform tumor necrosis factor receptor superfamily member 10A/B tumor necrosis factor ligand superfamily member 5 insulin receptor-related receptor tumor necrosis factor receptor type 1-associated DEATH domain protein CDK2-related kinase cytochrome c catenin beta-1 caspase-8-like protease caspase-3-like protease caspase-1-like protease apoptotic protease-activating factor 1 apoptosis regulator BAX TNF receptor-associated factor RAC-alpha serine/threonine-protein kinase tumor necrosis factor ligand superfamily member 4 ikaros-like zinc finger transcription factor tumor necrosis factor ligand superfamily member 13B tumor necrosis factor ligand superfamily member 13 tumor necrosis factor ligand superfamily member 10/11 transferrin receptor protein 1 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 transcription factor PU.1 transcription factor E2-alpha lymphocyte antigen 76 transcription factor COE1 trans-actingT-cell-specific transcription factor GATA-3 tissue factor collagen alpha chain FADD protein DNA fragmentation factor subunit alpha probable G-protein coupled receptor 157 Bcl2-like protein 11 Bcl2-like apoptosis inhibitor Bcl2 homologous antagonist/killer probable G protein-coupled receptor 123 Bcl2 antagonist of cell death BH3-interacting domain death agonist 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 2 thrombopoietin receptor thrombomodulin-like receptor ly-6-like protein tartrate-resistant acid phosphatase type 5 syndecan-3 syndecan-1 ataxin-1/ataxin-1-like sodium/potassium-transporting ATPase subunit beta-3 signal transducer and transcription activator STAT signal transducer CD24 neural cell adhesion molecule-like protein sialoadhesin neprilysin sialic acid-binding Ig-like lectin 8 natural killer cell receptor NKG2 natural killer cell receptor 2B4 natural cytotoxicity triggering receptor 3 antithrombin-III natural cytotoxicity triggering receptor 2 natural cytotoxicity triggering receptor 1 myeloid cell surface antigen CD33 serine/threonine-protein kinase, MST4-like 26S proteasome non-ATPase regulatory subunit 13 rho GTPase-activating protein 10 multidrug resistance protein 1 mucin-1 26S proteasome non-ATPase regulatory subunit 12 protein kinase C, delta-like 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 1 toll-like receptor rhodopsin-like G protein-coupled receptor sialic acid-binding Ig-like lectin 7 lymphocyte function-associated antigen 3 sialic acid-binding Ig-like lectin 6 interleukin-17 sialic acid-binding Ig-like lectin 5 semaphorin interleukin-1 immunoglobulin superfamily member 8 scavenger receptor cysteine-rich type 1 protein M130 receptor-type tyrosine-protein phosphatase eta receptor-type tyrosine-protein kinase Tie putative mucin core protein 24 protein jagged-1 monocyte differentiation antigen CD14 proteasome subunit beta type-4 proteasome subunit beta type-2 prostaglandin F2 receptor negative regulator membrane alanyl aminopeptidase-like metallopeptidase melanotransferrin occludin mitogen-activated protein kinase 8 RAF proto-oncogene serine/threonine-protein kinase major prion protein macrophage scavenger receptor types I and II DNA-binding protein A macrophage receptor MARCO lysosome-associated membrane protein glycylpeptide N-tetradecanoyltransferase 1 lysosome-associated membrane glycoprotein 3 gelsolin lymphocyte activation gene 3 protein dynein light chain low affinity immunoglobulin epsilon Fc receptor calcium-independent alpha-latrotoxin receptor immunoglobulin superfamily member 2 alpha-latrotoxin VVC2C2C2 Ig-like domain arrangement-containing protein T-cell surface glycoprotein CD8 beta chain T-cell surface glycoprotein CD8 alpha chain programmed cell death protein 1 T-cell surface glycoprotein CD2 pre T-cell antigen receptor alpha CD160 antigen potassium channel, TWIK-1-related potassium channel subfamily T potassium channel subfamily K member 5 potassium channel subfamily K member 2 potassium channel subfamily K member 16 (human) potassium channel subfamily K member 10 leukosialin poliovirus receptor-related protein 14-3-3 protein plexin-C1 leukocyte-associated immunoglobulin-like receptor 2 leukocyte-associated immunoglobulin-like receptor 1 leukemia inhibitory factor receptor leptin receptor killer cell lectin-like receptor subfamily B member 1 kell blood group glycoprotein junctional adhesion molecule B caveolin-1 calcium/calmodulin-dependent protein kinase II chain junctional adhesion molecule A islet cell autoantigen 1 NAD(P)+--arginine ADP-ribosyltransferase platelet glycoprotein V platelet glycoprotein Ib beta chain platelet glycoprotein Ib alpha chain platelet glycoprotein IX tumor necrosis factor, TNF-like platelet glycoprotein 4 transcription factor Sp transcription adapter with TAZ, KIX and bromo-domains platelet endothelial cell adhesion molecule thrombospondin subgroup B paired box protein PAX-5 nuclear receptor ROR-gamma nitric-oxide synthase, inducible interleukin-7 receptor subunit alpha interleukin-6 receptor subunit beta neuropilin-1 envelope glycoprotein gp160 interleukin-5 receptor subunit alpha interleukin-4 receptor alpha chain interleukin-3 receptor class 2 alpha chain interferon-induced transmembrane protein interferon regulatory factor 3-9 interferon regulatory factor 1/2 myosin light chain integrin beta inducible T-cell costimulator thrombospondin subgroup A small GTPase smad protein smad anchor for receptor activation ribosomal protein S6 kinase beta rho-associated protein kinase retinoblastoma-like protein ptx homeobox protein noggin protein myc protein immunoglobulin lambda-like polypeptide 1 immunoglobulin iota chain immunoglobulin alpha Fc receptor mitogen-activated protein kinase kinase kinase 1 ski oncogene hyaluronan mediated motility receptor fractalkine ectonucleoside triphosphate diphosphohydrolase 1 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B cytotoxic T-lymphocyte protein 4 cell surface antigen 4F2 heavy chain shc-transforming protein cathepsin K NEDD4-like E3 ubiquitin-protein ligase WWP1 IGFBP-related protein mitogen-activated protein kinase latent TGF-beta-binding protein interferon gamma HECT-domain-containing E3 ubiquitin-protein ligase with WW domains follistatin cyclin-dependent kinase inhibitor cullin creb-binding protein/zinc finger protein HRX chimera class 1 small leucine-rich proteoglycan chordin conventional serine/threonine-protein phosphatase calcium-activated potassium channel subunit alpha-1 butyrophilin band 3-like protein serine-threonine kinase receptor-associated protein arginase-1 Thy-1 membrane glycoprotein T-lymphocyte surface antigen Ly-9 T-cell-specific surface glycoprotein CD28 T-cell surface protein tactile spectrin beta subunit transforming growth factor-beta receptor-associated protein 1 anti-Muellerian hormone type-2 receptor TGF-beta-like cystine-knot cytokine TGF-beta superfamily receptor type-2 with activin receptor domain TGF-beta superfamily receptor type-1 cystic fibrosis transmembrane conductance regulator (cftr) TGF-beta receptor type-2 Na(+)/H(+) exchange regulatory cofactor with ERM-binding domain RING-box protein HLH DNA-binding protein inhibitor E3 ubiquitin ligase SFC complex Skp1 subunit T-cell surface glycoprotein CD5 T-cell surface glycoprotein CD1 T-cell differentiation antigen CD6 T-cell antigen CD7 T-box transcription factor TBX21 SLAM family member 7 SLAM family member 1 SIRP/SHPS-1 family protein mitogen-activated protein kinase kinase kinase 7 PR-domain zinc finger protein 1 P-selectin glycoprotein ligand 1 UBA domain-containing ubiquitin-conjugating enzyme E2 leukocyte surface antigen CD47 leukocyte immunoglobulin-like receptor subfamily A member 4 interleukin-9 receptor interleukin-9 ww domain-containing oxidoreductase interleukin-8 interleukin-6 receptor subunit alpha interleukin-6 interleukin-5 interleukin-4 interleukin-34 erm protein OX-2 membrane glycoprotein NKG2-D type II integral membrane protein NADPH oxidase 5 NADPH oxidase 4 NADPH oxidase 3 NADPH oxidase 1 MHC class II transactivator MHC class II histocompatibility antigen gamma chain MHC class II histocompatibility antigen beta chain TRAF family member-associated NF-kappa-B activator MHC class II histocompatibility antigen alpha chain prominin protein pellino interleukin-1 receptor-associated kinase IRAK1/3 interleukin-33 interleukin-1 receptor-associated kinase 4 interleukin-32 interleukin-3 CD247 interleukin-27 subunit beta interleukin-27 subunit alpha C-type lectin with multiple lectin domains interleukin-23 subunit alpha interleukin-22 interleukin-21 neural cell adhesion molecule interleukin-2 receptor subunit beta interleukin-2 receptor subunit alpha MHC class I-related gene protein MHC class I histocompatibility antigen alpha chain LDL receptor-related protein HGF/MSP receptor type tyrosine-protein kinase G protein-activated inward rectifier potassium channel EGF-like module-containing mucin-like hormone receptor-like 1 EGF receptor type tyrosine-protein kinase subtilisin/kexin-type proprotein convertase CSF-1/PDGF receptor-type tyrosine-protein kinase IKK-related kinase inhibitor of nuclear factor kappa-B kinase complex alpha/beta subunits lipopolysaccharide-binding protein diablo homolog, mitochondrial interleukin-2 vascular endothelial growth factor B mitogen-activated protein kinase kinase kinase 7-interacting protein 1 interleukin-18 receptor accessory protein CD3 subunit with immunoglobulin domain interleukin-18 receptor 1 interleukin-18 interleukin-17 receptor A interleukin-16 interleukin-15 cyclin-dependent kinase inhibitor 1B interleukin-13 receptor alpha-2 chain interleukin-13 receptor alpha-1 chain interleukin-13 CD59 glycoprotein C/C-C motif small inducible chemokine C-type lectin domain family 7 member A C-type lectin domain family 6 member A C-X-C motif chemokine 17 C-X-C motif chemokine 16 C-C motif chemokine 28 C-C motif chemokine 27 C-C motif chemokine 25 mitogen-activated protein kinase kinase kinase 7-interacting protein 2/3 baculoviral IAP repeat-containing protein 7 5'-nucleotidase Bcl-2-binding component 3 tumor-associated calcium signal transducer tumor necrosis factor receptor superfamily member 17 tumor necrosis factor receptor superfamily member 16 tumor necrosis factor ligand superfamily member 8 tetraspanin natural killer cells antigen CD94 interleukin-12 subunit beta membrane cofactor protein interleukin-12 subunit alpha interleukin-12 receptor beta 1 interleukin-11 leukocyte common antigen CD45 interleukin-10 receptor alpha chain voltage-gated potassium channel alpha subunit integrin alpha with A domain interleukin-1 receptor type II CD4 voltage-gated potassium channel subunit KQT interleukin-1 receptor type I interferon lambda voltage-gated potassium channel alpha subunit KCNA4 CD34 CD19 antigen voltage-gated potassium channel alpha subunit with PAS domain interferon gamma receptor alpha chain transient receptor potential cation channel TRPV intercellular adhesion molecule 5 transient receptor potential cation channel TRPC baculoviral IAP repeat-containing protein 4 proto-oncogene vav NFAT protein transcription factor NF-kappa-B NF-kappa-B essential modulator TGF-beta receptor type-3 toll/interleukin-1 receptor domain-containing adapter protein intercellular adhesion molecule 4 TIR domain-containing adapter molecule 2 intercellular adhesion molecule 2 transient receptor potential cation channel TRPA intercellular adhesion molecule 1/3 sodium leak channel non-selective protein shab-related voltage-gated potassium channel alpha subunit immunoglobulin gamma Fc receptor I potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel protein immunoglobulin gamma Fc receptor II/III/IV platelet-derived growth factor with CUB domain granulocyte-macrophage colony-stimulating factor receptor subunit alpha granulocyte colony-stimulating factor receptor cyclic nucleotide-gated channel beta subunit cyclic nucleotide-gated channel alpha subunit glycophorin cation channel sperm-associated protein subunit beta gamma-glutamyltranspeptidase cation channel sperm-associated protein 3 forkhead box protein P3 cation channel sperm-associated protein 2 TIR domain-containing adapter molecule map kinase p38 translocation-associated membrane protein myeloid differentiation primary response protein MyD88 fibroblast growth factor receptor erythrocyte membrane protein Rh cation channel sperm-associated protein 1 endothelial protein C receptor calcium-activated calmodulin-binding potassium channel alpha subunit SYK/ZAP-70 family tyrosine-protein kinase endosialin endoglin ectonucleotide pyrophosphatase/phosphodiesterase 3 early activation antigen CD69 discoidin domain-containing receptor dipeptidyl-peptidase IV cytokine receptor common gamma chain conventional protein kinase C cytokine receptor common beta chain complement receptor type 2 complement receptor type 1 complement decay-accelerating factor class 2 cytokine, IL-10 type choline transporter-like protein 1 transmembrane protease, serine 9 cation-independent mannose 6-phosphate receptor carcinoembryonic antigen-related cell adhesion molecule 8 carcinoembryonic antigen-related cell adhesion molecule 6 CD180 antigen carcinoembryonic antigen-related cell adhesion molecule 5 CD177 antigen CD109 antigen CAMPATH-1 antigen C-type lectin domain family 4 member M C-type lectin domain family 4 member K C-type lectin domain family 4 member C C-type asialoglycoprotein receptor B7-related protein carcinoembryonic antigen-related cell adhesion molecule 3 carcinoembryonic antigen-related cell adhesion molecule 1 kinesin-like protein KIF11 cadherin mitogen-activated protein kinase kinase kinase kinase 4 bone marrow stromal antigen 2 beta-1,3-glucuronyltransferase basigin serine/threonine-protein kinase mTOR autoimmune regulator angiotensin-converting enzyme, somatic isoform B-cell surface antigen CD20 alpha-taxilin B-cell receptor CD22 alpha-(1,3)-fucosyltransferase B-cell differentiation antigen CD72 B-cell antigen receptor complex-associated protein beta-chain B-cell antigen receptor complex-associated protein alpha-chain B- and T-lymphocyte attenuator ATP-binding cassette sub-family G member 2 ALK receptor tyrosine kinase ADP-ribosyl cyclase ADAM 8 endopeptidase transient receptor potential cation channel TRPM8 SLAM family member 5 L-selectin cellular tumor antigen p53 interleukin-7 interleukin-31 leucine-rich repeat serine/threonine-protein kinase 2 G protein-coupled receptor frizzled Fc receptor-like protein 5 E/P-selectin focal adhesion kinase CD99 antigen ADAM 17 endopeptidase CD97 antigen CD83 antigen ADAM 10 endopeptidase CD70 antigen CD48 antigen CD44 antigen CD320 antigen CD302 antigen CD300 antigen-like protein CD226 antigen CD209 antigen-like protein A CD209 antigen prostate-specific antigen chondrocalcin voltage-gated sodium channel subunit alpha voltage-gated calcium channel subunit alpha voltage-dependent T-type calcium channel subunit alpha-1I voltage-dependent T-type calcium channel subunit alpha-1G vascular endothelial growth factor receptor vascular cell adhesion protein 1 lymphocyte antigen 96 NF-kappaB inhibitor ubiquitin-conjugating enzyme variant urokinase plasminogen activator surface receptor tyrosine-protein phosphatase non-receptor type substrate 1 tyrosine-protein kinase TEC-type two pore calcium channel protein 2 suppressor of fused homolog tumor necrosis factor receptor superfamily member 9 tumor necrosis factor receptor superfamily member 8 tumor necrosis factor receptor superfamily member 7 lysine-specific histone demethylase 1B tumor necrosis factor receptor superfamily member 6 typical ubiquitin-conjugating enzyme E2 tumor necrosis factor receptor superfamily member 5 tumor necrosis factor receptor superfamily member 4 TRAF-interacting protein with FHA domain-containing protein dual specificity mitogen-activated protein kinase kinase 3 dual specificity mitogen-activated protein kinase kinase 4 |
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