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International Classification of Primary Care| ID: | PRO:000001719 |
| Full Id: | |
| Synonyms: | "Trpm8" "TRPP8" "Long transient receptor potential channel 6" "LTrpC6" "Transient receptor potential cation channel subfamily M member 8" "Transient receptor potential-p8" "Trp-p8" |
| Definitions: | A protein that is a translation product of the TRPM8 gene. TRPM8 is a member of the subfamily M of the transient receptor potential cation channels (TRPs). In common with other TRPs, these proteins have amino- and carboxyl-terminal intracellular domains separated by a domain containing six transmembrane helices (S1-S6) in which the last two helices (S5 and S6) flank a loop, called the pore loop, which determines ion selectivity.nTRPM8 forms a nonselective cation channel that is activated by cold and by menthol and other substances that produce the sensation of coolness. These channels exhibit voltage-dependance and regulation by phosphatidylinositol-4,5-bisphosphate (PIP2). |
| Comment: |
Category=gene. |
| Database References: | PIRSF |
| Exact Synonym: | "Long transient receptor potential channel 6" "LTrpC6" "Transient receptor potential cation channel subfamily M member 8" "Transient receptor potential-p8" "Trp-p8" |
| Related Synonym: | "Trpm8" "TRPP8" |
| Is A: | protein |
| Subject | Subject Sort | Author | Type | Target | Created |
|---|---|---|---|---|---|
| No notes to display |
| Subject | Subject Sort | Author | Type | Target | Created |
|---|
| Mapping To | Source | Relationship Type | Mapped By | Mapped On | Notes |
|---|---|---|---|---|---|
| TRPM8 (NIFSTD) | LOOM | lexical similarity | amirg | 05/17/10 | View Notes |
| transient receptor potential cation channel TRPM8 (NIFSTD) | LOOM | direct reference | amirg | 05/17/10 | View Notes |
: Relationship is "IS_A"
: Relationship is "PART_OF"





