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PRotein Ontology (PRO)

Version 1.13

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel protein | Link Here | Subscribe

View Ontology Summary

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- natural, non-standard encoded residue
  - {url:/ajax_concepts/40094/?id=MOD%3A00868&callback=children}
- post-translational protein modification
  - {url:/ajax_concepts/40094/?id=PRO%3A000002967&callback=children}
- protein
  - 14-3-3 protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000002175&callback=children}
  - 26S proteasome non-ATPase regulatory subunit 1
    - {url:/ajax_concepts/40094/?id=PRO%3A000002176&callback=children}
  - 26S proteasome non-ATPase regulatory subunit 11
    - {url:/ajax_concepts/40094/?id=PRO%3A000002177&callback=children}
  - 26S proteasome non-ATPase regulatory subunit 12
    - {url:/ajax_concepts/40094/?id=PRO%3A000002178&callback=children}
  - 26S proteasome non-ATPase regulatory subunit 13
    - {url:/ajax_concepts/40094/?id=PRO%3A000002179&callback=children}
  - 26S proteasome non-ATPase regulatory subunit 2
    - {url:/ajax_concepts/40094/?id=PRO%3A000002180&callback=children}
  - 26S proteasome non-ATPase regulatory subunit 4
    - {url:/ajax_concepts/40094/?id=PRO%3A000002181&callback=children}
  - 26S proteasome non-ATPase regulatory subunit 6
    - {url:/ajax_concepts/40094/?id=PRO%3A000002182&callback=children}
  - 5'-nucleotidase
    - {url:/ajax_concepts/40094/?id=PRO%3A000001800&callback=children}
  - ADAM 10 endopeptidase
  - ADAM 17 endopeptidase
  - ADAM 8 endopeptidase
  - ADP-ribosyl cyclase
    - {url:/ajax_concepts/40094/?id=PRO%3A000001281&callback=children}
  - ALK receptor tyrosine kinase
  - alpha-(1,3)-fucosyltransferase
    - {url:/ajax_concepts/40094/?id=PRO%3A000001320&callback=children}
  - alpha-latrotoxin
    - {url:/ajax_concepts/40094/?id=PRO%3A000001088&callback=children}
  - alpha-taxilin
  - angiotensin-converting enzyme, somatic isoform
  - anti-Muellerian hormone type-2 receptor
    - {url:/ajax_concepts/40094/?id=PRO%3A000000009&callback=children}
  - apoptosis regulator BAX
    - {url:/ajax_concepts/40094/?id=PRO%3A000002193&callback=children}
  - apoptotic protease-activating factor 1
    - {url:/ajax_concepts/40094/?id=PRO%3A000002194&callback=children}
  - arginase-1
  - ATP-binding cassette sub-family G member 2
  - autoimmune regulator
  - B- and T-lymphocyte attenuator
  - B-cell antigen receptor complex-associated protein alpha-chain
  - B-cell antigen receptor complex-associated protein beta-chain
  - B-cell differentiation antigen CD72
  - B-cell receptor CD22
  - B-cell surface antigen CD20
  - B7-related protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000001290&callback=children}
  - band 3-like protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000001845&callback=children}
  - basigin
    - {url:/ajax_concepts/40094/?id=PRO%3A000001324&callback=children}
  - Bcl2 antagonist of cell death
    - {url:/ajax_concepts/40094/?id=PRO%3A000002184&callback=children}
  - Bcl2 homologous antagonist/killer
    - {url:/ajax_concepts/40094/?id=PRO%3A000002185&callback=children}
  - Bcl2-like apoptosis inhibitor
    - {url:/ajax_concepts/40094/?id=PRO%3A000002186&callback=children}
  - Bcl2-like protein 11
    - {url:/ajax_concepts/40094/?id=PRO%3A000002187&callback=children}
  - beta-1,3-glucuronyltransferase
    - {url:/ajax_concepts/40094/?id=PRO%3A000001325&callback=children}
  - BH3-interacting domain death agonist
    - {url:/ajax_concepts/40094/?id=PRO%3A000002183&callback=children}
  - bone marrow stromal antigen 2
  - butyrophilin
    - {url:/ajax_concepts/40094/?id=PRO%3A000001848&callback=children}
  - C-C motif chemokine 25
  - C-C motif chemokine 27
  - C-C motif chemokine 28
  - C-type asialoglycoprotein receptor
    - {url:/ajax_concepts/40094/?id=PRO%3A000001291&callback=children}
  - C-type lectin domain family 4 member C
  - C-type lectin domain family 4 member K
  - C-type lectin domain family 4 member M
  - C-type lectin domain family 6 member A
  - C-type lectin domain family 7 member A
  - C-type lectin with multiple lectin domains
    - {url:/ajax_concepts/40094/?id=PRO%3A000001025&callback=children}
  - C-X-C motif chemokine 16
  - C-X-C motif chemokine 17
  - C/C-C motif small inducible chemokine
    - {url:/ajax_concepts/40094/?id=PRO%3A000001808&callback=children}
  - cadherin
    - {url:/ajax_concepts/40094/?id=PRO%3A000001327&callback=children}
  - calcium-activated calmodulin-binding potassium channel, alpha subunit
    - {url:/ajax_concepts/40094/?id=PRO%3A000000668&callback=children}
  - calcium-activated potassium channel subunit alpha-1
  - calcium-independent alpha-latrotoxin receptor
    - {url:/ajax_concepts/40094/?id=PRO%3A000001124&callback=children}
  - CAMPATH-1 antigen
  - carcinoembryonic antigen-related cell adhesion molecule 1
  - carcinoembryonic antigen-related cell adhesion molecule 3
  - carcinoembryonic antigen-related cell adhesion molecule 5
  - carcinoembryonic antigen-related cell adhesion molecule 6
  - carcinoembryonic antigen-related cell adhesion molecule 8
  - caspase-1-like protease
    - {url:/ajax_concepts/40094/?id=PRO%3A000002195&callback=children}
  - caspase-3-like protease
    - {url:/ajax_concepts/40094/?id=PRO%3A000002196&callback=children}
  - caspase-8-like protease
    - {url:/ajax_concepts/40094/?id=PRO%3A000002197&callback=children}
  - catenin beta-1
    - {url:/ajax_concepts/40094/?id=PRO%3A000002198&callback=children}
  - cathepsin K
  - cation channel sperm-associated protein 1
    - {url:/ajax_concepts/40094/?id=PRO%3A000000669&callback=children}
  - cation channel sperm-associated protein 2
    - {url:/ajax_concepts/40094/?id=PRO%3A000000670&callback=children}
  - cation channel sperm-associated protein 3
    - {url:/ajax_concepts/40094/?id=PRO%3A000000671&callback=children}
  - cation channel sperm-associated protein, subunit beta
    - {url:/ajax_concepts/40094/?id=PRO%3A000000672&callback=children}
  - cation-independent mannose 6-phosphate receptor
  - CD109 antigen
  - CD160 antigen
  - CD177 antigen
  - CD180 antigen
  - CD19 antigen
  - CD209 antigen
  - CD209 antigen-like protein A
  - CD226 antigen
  - CD247
    - {url:/ajax_concepts/40094/?id=PRO%3A000001027&callback=children}
  - CD3 subunit with immunoglobulin domain
    - {url:/ajax_concepts/40094/?id=PRO%3A000001018&callback=children}
  - CD300 antigen-like protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000001304&callback=children}
  - CD302 antigen
  - CD320 antigen
  - CD34
  - CD4
  - CD44 antigen
  - CD48 antigen
  - CD59 glycoprotein
    - {url:/ajax_concepts/40094/?id=PRO%3A000001809&callback=children}
  - CD70 antigen
  - CD83 antigen
  - CD97 antigen
  - CD99 antigen
  - cell surface antigen 4F2 heavy chain
  - choline transporter-like protein 1
  - chordin
    - {url:/ajax_concepts/40094/?id=PRO%3A000000010&callback=children}
  - class 1 small leucine-rich proteoglycan
    - {url:/ajax_concepts/40094/?id=PRO%3A000000011&callback=children}
  - class 2 cytokine, IL-10 type
    - {url:/ajax_concepts/40094/?id=PRO%3A000001335&callback=children}
  - complement decay-accelerating factor
  - complement receptor type 1
  - complement receptor type 2
  - creb-binding protein/zinc finger protein HRX chimera
    - {url:/ajax_concepts/40094/?id=PRO%3A000000012&callback=children}
  - CSF-1/PDGF receptor-type tyrosine-protein kinase
    - {url:/ajax_concepts/40094/?id=PRO%3A000001810&callback=children}
  - cullin
    - {url:/ajax_concepts/40094/?id=PRO%3A000000013&callback=children}
  - cyclic nucleotide-gated channel, alpha subunit
    - {url:/ajax_concepts/40094/?id=PRO%3A000000673&callback=children}
  - cyclic nucleotide-gated channel, beta subunit
    - {url:/ajax_concepts/40094/?id=PRO%3A000000674&callback=children}
  - cyclin-dependent kinase inhibitor
    - {url:/ajax_concepts/40094/?id=PRO%3A000000014&callback=children}
  - cystic fibrosis transmembrane conductance regulator (cftr)
    - {url:/ajax_concepts/40094/?id=PRO%3A000001044&callback=children}
  - cytochrome c
    - {url:/ajax_concepts/40094/?id=PRO%3A000002199&callback=children}
  - cytokine receptor common beta chain
  - cytokine receptor common gamma chain
  - cytotoxic T-lymphocyte protein 4
  - dipeptidyl-peptidase IV
  - discoidin domain-containing receptor
    - {url:/ajax_concepts/40094/?id=PRO%3A000001342&callback=children}
  - DNA fragmentation factor subunit alpha
    - {url:/ajax_concepts/40094/?id=PRO%3A000002188&callback=children}
  - DNA-binding protein Ikaros
    - {url:/ajax_concepts/40094/?id=PRO%3A000001811&callback=children}
  - dynein light chain
    - {url:/ajax_concepts/40094/?id=PRO%3A000002201&callback=children}
  - E/P-selectin
    - {url:/ajax_concepts/40094/?id=PRO%3A000001313&callback=children}
  - E3 ubiquitin ligase SFC complex, Skp1 subunit
    - {url:/ajax_concepts/40094/?id=PRO%3A000000002&callback=children}
  - early activation antigen CD69
  - ectonucleoside triphosphate diphosphohydrolase 1
  - ectonucleotide pyrophosphatase/phosphodiesterase 3
  - EGF receptor type tyrosine-protein kinase
    - {url:/ajax_concepts/40094/?id=PRO%3A000001812&callback=children}
  - EGF-like module-containing mucin-like hormone receptor-like 1
  - endoglin
  - endosialin
  - endothelial protein C receptor
  - erm protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000001030&callback=children}
  - erythrocyte membrane protein Rh
    - {url:/ajax_concepts/40094/?id=PRO%3A000001348&callback=children}
  - FADD protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000002189&callback=children}
  - Fc receptor-like protein 5
  - fibroblast growth factor receptor
    - {url:/ajax_concepts/40094/?id=PRO%3A000001349&callback=children}
  - follistatin
    - {url:/ajax_concepts/40094/?id=PRO%3A000000015&callback=children}
  - forkhead box protein P3
  - fractalkine
  - G protein-activated inward rectifier potassium channel
    - {url:/ajax_concepts/40094/?id=PRO%3A000001814&callback=children}
  - G protein-coupled receptor frizzled
    - {url:/ajax_concepts/40094/?id=PRO%3A000001315&callback=children}
  - gamma-glutamyltranspeptidase
    - {url:/ajax_concepts/40094/?id=PRO%3A000001351&callback=children}
  - gelsolin
    - {url:/ajax_concepts/40094/?id=PRO%3A000002202&callback=children}
  - glycophorin
    - {url:/ajax_concepts/40094/?id=PRO%3A000001352&callback=children}
  - glycylpeptide N-tetradecanoyltransferase 1
    - {url:/ajax_concepts/40094/?id=PRO%3A000002203&callback=children}
  - granulocyte colony-stimulating factor receptor
  - granulocyte-macrophage colony-stimulating factor receptor subunit alpha
  - HECT-domain-containing E3 ubiquitin-protein ligase with WW domains
    - {url:/ajax_concepts/40094/?id=PRO%3A000000016&callback=children}
  - HGF/MSP receptor type tyrosine-protein kinase
    - {url:/ajax_concepts/40094/?id=PRO%3A000001816&callback=children}
  - HLH DNA-binding protein inhibitor
    - {url:/ajax_concepts/40094/?id=PRO%3A000000003&callback=children}
  - hyaluronan mediated motility receptor
  - IKK-related kinase
    - {url:/ajax_concepts/40094/?id=PRO%3A000001777&callback=children}
  - immunoglobulin alpha Fc receptor
  - immunoglobulin gamma Fc receptor I
    - {url:/ajax_concepts/40094/?id=PRO%3A000001356&callback=children}
  - immunoglobulin gamma Fc receptor II/III/IV
    - {url:/ajax_concepts/40094/?id=PRO%3A000001355&callback=children}
  - immunoglobulin iota chain
  - immunoglobulin lambda-like polypeptide 1
  - immunoglobulin superfamily member 2
  - immunoglobulin superfamily member 8
  - inducibleT-cell costimulator
  - inhibitor of nuclear factor kappa-B kinase complex, alpha/beta subunits
    - {url:/ajax_concepts/40094/?id=PRO%3A000001774&callback=children}
  - integrin alpha with A domain
    - {url:/ajax_concepts/40094/?id=PRO%3A000001005&callback=children}
  - integrin beta
    - {url:/ajax_concepts/40094/?id=PRO%3A000001861&callback=children}
  - intercellular adhesion molecule 1/3
    - {url:/ajax_concepts/40094/?id=PRO%3A000001357&callback=children}
  - intercellular adhesion molecule 2
  - intercellular adhesion molecule 4
  - intercellular adhesion molecule 5
  - interferon gamma
    - {url:/ajax_concepts/40094/?id=PRO%3A000000017&callback=children}
  - interferon gamma receptor alpha chain
  - interferon lambda
    - {url:/ajax_concepts/40094/?id=PRO%3A000001362&callback=children}
  - interferon regulatory factor 1/2
    - {url:/ajax_concepts/40094/?id=PRO%3A000001862&callback=children}
  - interferon regulatory factor 3-9
    - {url:/ajax_concepts/40094/?id=PRO%3A000001863&callback=children}
  - interferon-induced transmembrane protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000001864&callback=children}
  - interleukin-1
    - {url:/ajax_concepts/40094/?id=PRO%3A000001091&callback=children}
  - interleukin-1 receptor type I
  - interleukin-1 receptor type II
  - interleukin-1 receptor-associated kinase 4
  - interleukin-1 receptor-associated kinase IRAK1/3
    - {url:/ajax_concepts/40094/?id=PRO%3A000001781&callback=children}
  - interleukin-10 receptor, alpha chain
  - interleukin-11
  - interleukin-12 receptor beta 1
  - interleukin-12, subunit alpha
  - interleukin-12, subunit beta
  - interleukin-13
  - interleukin-13 receptor alpha-1 chain
  - interleukin-13 receptor alpha-2 chain
  - interleukin-15
  - interleukin-16
  - interleukin-17
    - {url:/ajax_concepts/40094/?id=PRO%3A000001092&callback=children}
  - interleukin-17 receptor A
  - interleukin-18
  - interleukin-18 receptor 1
  - interleukin-18 receptor accessory protein
  - interleukin-2
  - interleukin-2 receptor alpha chain
  - interleukin-2 receptor beta chain
  - interleukin-21
  - interleukin-22
  - interleukin-23 subunit alpha
  - interleukin-27 subunit alpha
  - interleukin-27 subunit beta
  - interleukin-3
  - interleukin-3 receptor class 2 alpha chain
  - interleukin-31
  - interleukin-32
  - interleukin-33
  - interleukin-34
  - interleukin-4
  - interleukin-4 receptor alpha chain
  - interleukin-5
  - interleukin-5 receptor alpha chain
  - interleukin-6
  - interleukin-6 receptor beta chain
  - interleukin-6 receptor subunit alpha
    - {url:/ajax_concepts/40094/?id=PRO%3A000001394&callback=children}
  - interleukin-7
  - interleukin-7 receptor alpha chain
  - interleukin-8
  - interleukin-9
  - interleukin-9 receptor
  - islet cell autoantigen 1
  - junctional adhesion molecule A
  - junctional adhesion molecule B
  - kell blood group glycoprotein
  - killer cell lectin-like receptor subfamily B member 1
  - L-selectin
  - latent TGF-beta-binding protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000000018&callback=children}
  - LDL receptor-related protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000001817&callback=children}
  - leptin receptor
  - leukemia inhibitory factor receptor
  - leukocyte common antigen CD45
    - {url:/ajax_concepts/40094/?id=PRO%3A000001006&callback=children}
  - leukocyte immunoglobulin-like receptor subfamily A member 4
  - leukocyte surface antigen CD47
  - leukocyte-associated immunoglobulin-like receptor 1
  - leukocyte-associated immunoglobulin-like receptor 2
  - leukosialin
  - lipopolysaccharide-binding protein
  - low affinity immunoglobulin epsilon Fc receptor
  - lymphocyte activation gene 3 protein
  - lymphocyte function-associated antigen 3
  - lysosome-associated membrane glycoprotein 3
  - lysosome-associated membrane protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000001883&callback=children}
  - macrophage receptor MARCO
  - macrophage scavenger receptor types I and II
  - major prion protein
  - melanotransferrin
  - membrane alanyl aminopeptidase-like metallopeptidase
    - {url:/ajax_concepts/40094/?id=PRO%3A000001888&callback=children}
  - membrane cofactor protein
  - MHC class I histocompatibility antigen alpha chain
    - {url:/ajax_concepts/40094/?id=PRO%3A000001818&callback=children}
  - MHC class I-related gene protein
  - MHC class II histocompatibility antigen alpha chain
    - {url:/ajax_concepts/40094/?id=PRO%3A000001820&callback=children}
  - MHC class II histocompatibility antigen beta chain
    - {url:/ajax_concepts/40094/?id=PRO%3A000001821&callback=children}
  - MHC class II histocompatibility antigen gamma chain
  - MHC class II transactivator
  - mitogen-activated protein kinase
    - {url:/ajax_concepts/40094/?id=PRO%3A000000019&callback=children}
  - mitogen-activated protein kinase 8
    - {url:/ajax_concepts/40094/?id=PRO%3A000002206&callback=children}
  - mitogen-activated protein kinase kinase kinase 7-interacting protein 1
  - mitogen-activated protein kinase kinase kinase 7-interacting protein 2/3
    - {url:/ajax_concepts/40094/?id=PRO%3A000001769&callback=children}
  - monocyte differentiation antigen CD14
    - {url:/ajax_concepts/40094/?id=PRO%3A000001889&callback=children}
  - mucin-1
  - multidrug resistance protein 1
  - myc protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000000020&callback=children}
  - myeloid cell surface antigen CD33
  - myeloid differentiation primary response protein MyD88
    - {url:/ajax_concepts/40094/?id=PRO%3A000001740&callback=children}
  - Na(+)/H(+) exchange regulatory cofactor with ERM-binding domain
    - {url:/ajax_concepts/40094/?id=PRO%3A000001043&callback=children}
  - NAD(P)+--arginine ADP-ribosyltransferase
    - {url:/ajax_concepts/40094/?id=PRO%3A000002156&callback=children}
  - NADPH oxidase 1
  - NADPH oxidase 3
  - NADPH oxidase 4
  - NADPH oxidase 5
  - natural cytotoxicity triggering receptor 1
  - natural cytotoxicity triggering receptor 2
  - natural cytotoxicity triggering receptor 3
  - natural killer cell receptor 2B4
  - natural killer cell receptor NKG2
    - {url:/ajax_concepts/40094/?id=PRO%3A000001897&callback=children}
  - natural killer cells antigen CD94
  - neprilysin
  - neural cell adhesion molecule
    - {url:/ajax_concepts/40094/?id=PRO%3A000001022&callback=children}
  - neural cell adhesion molecule-like protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000001899&callback=children}
  - neuropilin
  - NF-kappa-B essential modulator
    - {url:/ajax_concepts/40094/?id=PRO%3A000001752&callback=children}
  - nitric-oxide synthase, inducible
  - NKG2-D type II integral membrane protein
  - noggin protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000000021&callback=children}
  - nuclear receptor ROR-gamma
  - occludin
    - {url:/ajax_concepts/40094/?id=PRO%3A000002207&callback=children}
  - OX-2 membrane glycoprotein
  - P-selectin glycoprotein ligand 1
  - paired box protein PAX-5
  - platelet endothelial cell adhesion molecule
  - platelet glycoprotein 4
  - platelet glycoprotein Ib alpha chain
  - platelet glycoprotein Ib beta chain
  - platelet glycoprotein IX
  - platelet glycoprotein V
  - platelet-derived growth factor with CUB domain
    - {url:/ajax_concepts/40094/?id=PRO%3A000000675&callback=children}
  - plexin-C1
  - poliovirus receptor-related protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000001911&callback=children}
  - potassium channel subfamily K member 10
  - potassium channel subfamily K member 16 (human)
  - potassium channel subfamily K member 2
  - potassium channel subfamily K member 5
  - potassium channel subfamily T
    - {url:/ajax_concepts/40094/?id=PRO%3A000001916&callback=children}
  - potassium channel, TWIK-1-related
    - {url:/ajax_concepts/40094/?id=PRO%3A000001917&callback=children}
  - potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000000676&callback=children}
  - PR-domain zinc finger protein 1
  - pre T-cell antigen receptor alpha
  - probable G protein-coupled receptor 123
  - probable G-protein coupled receptor 157
  - programmed cell death protein 1
  - prominin
    - {url:/ajax_concepts/40094/?id=PRO%3A000001785&callback=children}
  - prostaglandin F2 receptor negative regulator
  - proteasome subunit beta type-2
    - {url:/ajax_concepts/40094/?id=PRO%3A000002208&callback=children}
  - proteasome subunit beta type-4
    - {url:/ajax_concepts/40094/?id=PRO%3A000002209&callback=children}
  - protein jagged-1
  - protein kinase C, delta-like
    - {url:/ajax_concepts/40094/?id=PRO%3A000002210&callback=children}
  - ptx homeobox protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000000022&callback=children}
  - putative mucin core protein 24
  - RAC-alpha serine/threonine-protein kinase
    - {url:/ajax_concepts/40094/?id=PRO%3A000002190&callback=children}
  - receptor-type tyrosine-protein kinase Tie
    - {url:/ajax_concepts/40094/?id=PRO%3A000001923&callback=children}
  - receptor-type tyrosine-protein phosphatase eta
    - {url:/ajax_concepts/40094/?id=PRO%3A000001924&callback=children}
  - retinoblastoma-like protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000000023&callback=children}
  - rho GTPase-activating protein 10
    - {url:/ajax_concepts/40094/?id=PRO%3A000002211&callback=children}
  - rho-associated protein kinase
    - {url:/ajax_concepts/40094/?id=PRO%3A000000024&callback=children}
  - rhodopsin-like G protein-coupled receptor
    - {url:/ajax_concepts/40094/?id=PRO%3A000001094&callback=children}
  - ribosomal protein S6 kinase beta
    - {url:/ajax_concepts/40094/?id=PRO%3A000000025&callback=children}
  - RING-box protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000000004&callback=children}
  - scavenger receptor cysteine-rich type 1 protein M130
  - semaphorin
    - {url:/ajax_concepts/40094/?id=PRO%3A000001926&callback=children}
  - serine/threonine-protein kinase, MST4-like
    - {url:/ajax_concepts/40094/?id=PRO%3A000002212&callback=children}
  - shab-related voltage-gated potassium channel, alpha subunit
    - {url:/ajax_concepts/40094/?id=PRO%3A000000677&callback=children}
  - sialic acid-binding Ig-like lectin 5
  - sialic acid-binding Ig-like lectin 6
  - sialic acid-binding Ig-like lectin 7
  - sialic acid-binding Ig-like lectin 8
  - sialoadhesin
  - signal transducer and transcription activator STAT
    - {url:/ajax_concepts/40094/?id=PRO%3A000001933&callback=children}
  - signal transducer CD24
  - SIRP/SHPS-1 family protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000001832&callback=children}
  - SLAM family member 1
  - SLAM family member 5
  - SLAM family member 7
  - smad anchor for receptor activation
    - {url:/ajax_concepts/40094/?id=PRO%3A000000026&callback=children}
  - smad protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000000027&callback=children}
  - small GTPase
    - {url:/ajax_concepts/40094/?id=PRO%3A000000028&callback=children}
  - sodium leak channel non-selective protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000000678&callback=children}
  - sodium/potassium-transporting ATPase subunit beta-3
  - syndecan-1
  - syndecan-3
  - T-box transcription factor TBX21
  - T-cell antigen CD7
  - T-cell differentiation antigen CD6
  - T-cell surface glycoprotein CD1
    - {url:/ajax_concepts/40094/?id=PRO%3A000001838&callback=children}
  - T-cell surface glycoprotein CD2
    - {url:/ajax_concepts/40094/?id=PRO%3A000001083&callback=children}
  - T-cell surface glycoprotein CD5
  - T-cell surface glycoprotein CD8 alpha chain
  - T-cell surface glycoprotein CD8 beta chain
  - T-cell surface protein tactile
  - T-cell-specific surface glycoprotein CD28
  - T-lymphocyte surface antigen Ly-9
  - tartrate-resistant acid phosphatase type 5
  - tetraspanin
  - TGF-beta receptor type-2
    - {url:/ajax_concepts/40094/?id=PRO%3A000000005&callback=children}
  - TGF-beta superfamily receptor type-1
    - {url:/ajax_concepts/40094/?id=PRO%3A000000006&callback=children}
  - TGF-beta superfamily receptor type-2 with activin receptor domain
    - {url:/ajax_concepts/40094/?id=PRO%3A000000007&callback=children}
  - TGF-beta-like cystine-knot cytokine
    - {url:/ajax_concepts/40094/?id=PRO%3A000000008&callback=children}
  - thrombomodulin-like receptor
    - {url:/ajax_concepts/40094/?id=PRO%3A000001938&callback=children}
  - thrombopoietin receptor
  - thrombospondin subgroup A
    - {url:/ajax_concepts/40094/?id=PRO%3A000000029&callback=children}
  - thrombospondin subgroup B
    - {url:/ajax_concepts/40094/?id=PRO%3A000000030&callback=children}
  - Thy-1 membrane glycoprotein
  - TIR domain-containing adapter molecule
  - TIR domain-containing adapter molecule 2
  - tissue factor
  - TNF receptor-associated factor
    - {url:/ajax_concepts/40094/?id=PRO%3A000002191&callback=children}
  - toll-like receptor
    - {url:/ajax_concepts/40094/?id=PRO%3A000001096&callback=children}
  - toll/interleukin-1 receptor domain-containing adapter protein
  - trans-actingT-cell-specific transcription factor GATA-3
  - transcription adapter with TAZ, KIX and bromo-domains
    - {url:/ajax_concepts/40094/?id=PRO%3A000000031&callback=children}
  - transcription factor COE1
  - transcription factor E2-alpha
  - transcription factor NF-kappa-B
    - {url:/ajax_concepts/40094/?id=PRO%3A000001753&callback=children}
  - transcription factor PU.1
  - transcription factor Sp
    - {url:/ajax_concepts/40094/?id=PRO%3A000000032&callback=children}
  - transferrin receptor protein 1
  - transient receptor potential cation channel TRPA
    - {url:/ajax_concepts/40094/?id=PRO%3A000000679&callback=children}
  - transient receptor potential cation channel TRPC
    - {url:/ajax_concepts/40094/?id=PRO%3A000000680&callback=children}
  - transient receptor potential cation channel TRPM8
    - {url:/ajax_concepts/40094/?id=PRO%3A000001719&callback=children}
  - transient receptor potential cation channel TRPV
    - {url:/ajax_concepts/40094/?id=PRO%3A000000681&callback=children}
  - translocation-associated membrane protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000001744&callback=children}
  - tumor necrosis factor ligand superfamily member 10/11
    - {url:/ajax_concepts/40094/?id=PRO%3A000001946&callback=children}
  - tumor necrosis factor ligand superfamily member 13
  - tumor necrosis factor ligand superfamily member 13B
  - tumor necrosis factor ligand superfamily member 4
  - tumor necrosis factor ligand superfamily member 5
  - tumor necrosis factor ligand superfamily member 8
  - tumor necrosis factor receptor superfamily member 10A/B
    - {url:/ajax_concepts/40094/?id=PRO%3A000001951&callback=children}
  - tumor necrosis factor receptor superfamily member 10C
  - tumor necrosis factor receptor superfamily member 10D
  - tumor necrosis factor receptor superfamily member 11A
  - tumor necrosis factor receptor superfamily member 12A
  - tumor necrosis factor receptor superfamily member 13B
  - tumor necrosis factor receptor superfamily member 13C
  - tumor necrosis factor receptor superfamily member 16
  - tumor necrosis factor receptor superfamily member 17
  - tumor necrosis factor receptor superfamily member 1A
    - {url:/ajax_concepts/40094/?id=PRO%3A000001958&callback=children}
  - tumor necrosis factor receptor superfamily member 1B
  - tumor necrosis factor receptor superfamily member 4
  - tumor necrosis factor receptor superfamily member 5
  - tumor necrosis factor receptor superfamily member 6
    - {url:/ajax_concepts/40094/?id=PRO%3A000001962&callback=children}
  - tumor necrosis factor receptor superfamily member 7
  - tumor necrosis factor receptor superfamily member 8
  - tumor necrosis factor receptor superfamily member 9
  - tumor necrosis factor receptor type 1-associated DEATH domain protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000002233&callback=children}
  - tumor necrosis factor, TNF-like
    - {url:/ajax_concepts/40094/?id=PRO%3A000000033&callback=children}
  - tumor-associated calcium signal transducer
    - {url:/ajax_concepts/40094/?id=PRO%3A000001407&callback=children}
  - two pore calcium channel protein 2
  - tyrosine-protein kinase TEC-type
    - {url:/ajax_concepts/40094/?id=PRO%3A000001967&callback=children}
  - tyrosine-protein phosphatase non-receptor type substrate 1
  - urokinase plasminogen activator surface receptor
  - vascular cell adhesion protein 1
  - vascular endothelial growth factor receptor
    - {url:/ajax_concepts/40094/?id=PRO%3A000001971&callback=children}
  - voltage-dependent T-type calcium channel subunit alpha-1G
  - voltage-dependent T-type calcium channel subunit alpha-1I
  - voltage-gated calcium channel subunit alpha
    - {url:/ajax_concepts/40094/?id=PRO%3A000001974&callback=children}
  - voltage-gated potassium channel alpha subunit with PAS domain
    - {url:/ajax_concepts/40094/?id=PRO%3A000000682&callback=children}
  - voltage-gated potassium channel subunit KQT
    - {url:/ajax_concepts/40094/?id=PRO%3A000000684&callback=children}
  - voltage-gated potassium channel, alpha subunit
    - {url:/ajax_concepts/40094/?id=PRO%3A000000685&callback=children}
  - voltage-gated potassium channel, alpha subunit KCNA4
    - {url:/ajax_concepts/40094/?id=PRO%3A000000683&callback=children}
  - voltage-gated sodium channel subunit alpha
    - {url:/ajax_concepts/40094/?id=PRO%3A000001975&callback=children}
  - VVC2C2C2 Ig-like domain arrangement-containing protein
    - {url:/ajax_concepts/40094/?id=PRO%3A000001086&callback=children}
  - ww domain-containing oxidoreductase
    - {url:/ajax_concepts/40094/?id=PRO%3A000001036&callback=children}
  - zinc finger protein aiolos
    - {url:/ajax_concepts/40094/?id=PRO%3A000001976&callback=children}
  - zinc finger protein helios
    - {url:/ajax_concepts/40094/?id=PRO%3A000002172&callback=children}

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Resource Index

ID:	PRO:000000676
Full Id:	PRO:000000676
Synonyms:	"f-channel" "HCN"
Definitions:	A protein with amino- and carboxyl-terminal intracellular domains separated by a domain (common with other ion channels) containing six transmembrane helices (S1-S6) in which the last two helices (S5 and S6) flank a loop, called the pore loop, which determines ion selectivity. The N-terminus has a conserved domain that is also present in other voltage-gated potassium and sodium channels. The carboxyl-terminal region contains the cyclic nucleotide-binding domain (CNBD). In addition, there is a structural element called the C-linker, the region connecting the CNBD to the S6 segment, which couples conformational changes in the ligand-binding domain to channel activation. Subunits combine to form the HCN channels. In common with CNG channels, HCN are cation channels that are modulated by cyclic nucleotide binding. Unlike CNG channels, HCN channels are voltage-gated, and are weakly selective for potassium. In contrast to most other voltage-gated channels, HCN channels open upon hyperpolarization and close at positive potential. HCN channels act as a pacemaker by regulating neuronal and cardiac firing rate, but also function as a regulator of membrane resting potential and resistance.
Comment:	Category=family.
Database References:	PIRSF
Exact Synonym:	"f-channel"
Related Synonym:	"HCN"
Is A:	protein
Sub Class:	potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

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"New Point-to-Point Mapping"

Mapping To	Source	Mapped By	Mapped On	Notes
hydrogen cyanide (Chemical entities of biological interest)	LOOM	amirg	08/13/09	View Notes

PRotein Ontology (PRO)

Version 1.13

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel protein | Link Here | Subscribe

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