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PRotein Ontology (PRO)

Version 1.13

cation channel sperm-associated protein 2 | Link Here | Subscribe


ID:

PRO:000000670

Full Id:

PRO:000000670

Synonyms:

"CatSper2"

Definitions:

A protein that is a translation product of the CATSPER2 gene. In mammals, four CatSper ion channel subunit genes (CatSpers 1-4) are required for sperm cell hyperactivation and male fertility. The four proteins assemble (presumably as a tetramer) to form a sperm-specific, alkalinization-activated Ca(2+)-selective channel. CatSper channels seem to require auxiliary subunits, such as CatSperB (PRO:000000672). In common with other channels, CatSper2 proteins have an architecture consisting of six transmembrane domains (S1-S6), arranged in a voltage sensor (S1-S4) and pore modules (S5-P-S6), and with both N and C termini on the intracellular side of the membrane.

Comment:

Category=gene.

Exact Synonym:

"CatSper2"

Is A:

protein

Sub Class:

cation channel sperm-associated protein 2 isoform 4

cation channel sperm-associated protein 2 isoform 3

cation channel sperm-associated protein 2 isoform 1

cation channel sperm-associated protein 2 isoform 2

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"New Point-to-Point Mapping"

Mapping To Source Mapped By Mapped On Notes
CatSper2 (NIFSTD) LOOM amirg 08/13/09 View Notes
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Release 2.3 (released February 3, 2010)