loading...| Preferred Name |
Hepatitis B surface antigen |
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| Synonyms |
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| Definitions |
Study compared a current HBV vaccine that contains recombinant hepatitis B surface antigen HBsAg) adsorbed to alum in chimpanzees, with two novel vaccine strategies that have proven superior to the current vaccine in mice. All animals receiving either control or CpG-containing subunit vaccines at 0 and 4 weeks attained titers of HBsAg-specific antibody (anti-HBs) considered protective (> or =10 mIU/ml) and were indeed protected from challenge at 8 weeks with 10(3.5) 50% chimp infectious doses (CID(50)) of intravenous HBV [PubMed: 16428890]. |
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| ID |
http://purl.obolibrary.org/obo/VO_0011093 |
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| comment |
Study compared a current HBV vaccine that contains recombinant hepatitis B surface antigen HBsAg) adsorbed to alum in chimpanzees, with two novel vaccine strategies that have proven superior to the current vaccine in mice. All animals receiving either control or CpG-containing subunit vaccines at 0 and 4 weeks attained titers of HBsAg-specific antibody (anti-HBs) considered protective (> or =10 mIU/ml) and were indeed protected from challenge at 8 weeks with 10(3.5) 50% chimp infectious doses (CID(50)) of intravenous HBV [PubMed: 16428890]. |
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| has role | ||
| inSubset |
protein |
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| label |
Hepatitis B surface antigen |
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| prefixIRI |
VO:0011093 |
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| prefLabel |
Hepatitis B surface antigen |
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| seeAlso |
Protegen ID: 495; NCBI Protein GI: 128168861; NCBITaxon: 10407 |
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| term editor |
YH, ZX |
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| subClassOf |