Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

Dandy-Walker malformation

Synonyms

Dandy-walker anomaly

Dandy-Walker cyst

Definitions

A congenital brain malformation typically characterized by incomplete formation of the cerebellar vermis, dilation of the fourth ventricle, and enlargement of the posterior fossa. In layman's terms, Dandy Walker malformation is a cyst in the cerebellum (typically symmetrical) that is involved with the fourth ventricle. This may interfere with the ability to drain cerebrospinal fluid from the brain, resulting in hydrocephalus. Dandy Walker cysts are formed during early embryonic development, while the brain forms. The cyst in the cerebellum typically has several blood vessels running through it connecting to the brain, thereby prohibiting surgical removal.

ID

http://purl.obolibrary.org/obo/HP_0001305

database_cross_reference

SNOMEDCT_US:14447001

UMLS:C0010964

MSH:D003616

definition

A congenital brain malformation typically characterized by incomplete formation of the cerebellar vermis, dilation of the fourth ventricle, and enlargement of the posterior fossa. In layman's terms, Dandy Walker malformation is a cyst in the cerebellum (typically symmetrical) that is involved with the fourth ventricle. This may interfere with the ability to drain cerebrospinal fluid from the brain, resulting in hydrocephalus. Dandy Walker cysts are formed during early embryonic development, while the brain forms. The cyst in the cerebellum typically has several blood vessels running through it connecting to the brain, thereby prohibiting surgical removal.

has exact synonym

Dandy-walker anomaly

Dandy-Walker cyst

has_alternative_id

HP:0001313

HP:0006809

id

HP:0001305

label

Dandy-Walker malformation

notation

HP:0001305

prefLabel

Dandy-Walker malformation

subClassOf

http://purl.obolibrary.org/obo/HP_0001320

http://purl.obolibrary.org/obo/HP_0005445

http://purl.obolibrary.org/obo/HP_0002198

http://purl.obolibrary.org/obo/MP_0000829

http://purl.obolibrary.org/obo/HP_0002350

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