Toxic Process Ontology

Last uploaded: August 20, 2019
Preferred Name

sulindac

Definitions

A monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the para position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions.

ID

http://purl.obolibrary.org/obo/CHEBI_9352

database_cross_reference

KEGG:D00120

ATC:M01AB02

KEGG:C01531

Wikipedia:Sulindac

definition

A monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the para position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions.

label

sulindac

sulindac

prefixIRI

CHEBI:9352

prefLabel

sulindac

smiles

CC1=C(CC(O)=O)c2cc(F)ccc2C1=C/c1ccc(cc1)S(C)=O

subClassOf

http://purl.obolibrary.org/obo/CHEBI_50860

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http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013467 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146307 NDFRT LOOM
http://www.co-ode.org/ontologies/galen#Sulindac GALEN LOOM
http://purl.bioontology.org/ontology/RCD/j2f.. RCD LOOM
http://scai.fraunhofer.de/AlzheimerOntology#sulindac ADO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C850 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C850 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C850 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C850 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C850 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.486.875 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D013467 MESH LOOM
http://stirdf.jst.go.jp/id/200907040615001920 IOBC LOOM
http://stirdf.jst.go.jp/id/200907040615001920 IOBC LOOM
http://stirdf.jst.go.jp/id/200907040615001920 IOBC LOOM
http://purl.bioontology.org/ontology/VANDF/4017957 VANDF LOOM
http://data.bnf.fr/ark:/12148/cb12562840g FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000041538 PDQ LOOM
http://purl.bioontology.org/ontology/LNC/LP18100-5 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.847.486.875 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9352 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_9352 EFO SAME_URI
http://d-nb.info/gnd/4358401-9 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/RXNORM/10237 RXNORM LOOM
http://id.loc.gov/authorities/subjects/sh85130323 FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387513000 SNOMEDCT LOOM
http://purl.jp/bio/4/id/200906008974470052 IOBC LOOM
http://purl.jp/bio/4/id/200906008974470052 IOBC LOOM
http://purl.jp/bio/4/id/200906008974470052 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003386 LOINC LOOM
http://www.drugbank.ca/drugs/DB00605 FTC LOOM
http://purl.bioontology.org/ontology/SNMI/C-60440 SNMI LOOM
http://purl.bioontology.org/ontology/UATC/M01AB02 ATC LOOM