The Stroke Ontology

Last uploaded: August 7, 2018
Preferred Name

Barbiturate

ID

http://www.semanticweb.org/ontologies/STO.owl#OWLClass_60f85153_5af2_4b13_bfb9_0328198e336b

hasDbXref

http://purl.bioontology.org/ontology/SNOMEDCT/372798009

isDefinedBy

Barbiturates in high doses are effective in lowering refractory intracranial hypertension but ineffective or potentially harmful as a first-line or prophylactic treatment in patients with brain injuries. High-dose barbiturate treatment acts by depressing cerebral metabolic activity. This results in a reduction in CBF, which is coupled to metabolism, and a fall in ICP.

label

Barbiturate

prefixIRI

OWLClass_60f85153_5af2_4b13_bfb9_0328198e336b

prefLabel

Barbiturate

references

Broderick, J., Connolly, S., Feldmann, E., Hanley, D., Kase, C., Krieger, D., ... & Zuccarello, M. (2007). Guidelines for the Management of Spontaneous Intracerebral Hemorrhage in Adults 2007 Update: A Guideline From the American Heart Association/American Stroke Association Stroke Council, High Blood Pressure Research Council, and the Quality of Care and Outcomes in Research Interdisciplinary Working Group: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Stroke, 38(6), 2001-2023.

subClassOf

http://www.semanticweb.org/ontologies/STO.owl#OWLClass_bcc5e203_ae50_432a_be9b_d5c673185bbe

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http://www.semanticweb.org/ontologies/STO.owl#OWLClass_bcd42ca4_3adf_4b93_bc2d_afdcb447c8e2 CVAO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#21195 OCHV LOOM
http://www.projecthalo.com/aura#Barbiturate AURA LOOM
http://purl.obolibrary.org/obo/CHEBI_29745 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_29745 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_29745 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_29745 NIFSTD LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_60f85153_5af2_4b13_bfb9_0328198e336b CVAO LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_60f85153_5af2_4b13_bfb9_0328198e336b CVAO SAME_URI
http://www.gamuts.net/entity#barbiturate GAMUTS LOOM
http://purl.obolibrary.org/obo/CHEBI_22693 NIFSTD LOOM
http://purl.bioontology.org/ontology/RCD/X794r RCD LOOM
http://purl.bioontology.org/ontology/LNC/LA28414-3 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0004745 OCHV LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67084 NCIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372798009 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/CSP/2517-5236 CRISP LOOM
http://purl.obolibrary.org/obo/UPa_UPC00813 UPA LOOM
http://purl.bioontology.org/ontology/LNC/LP16043-9 LOINC LOOM