Radiation Oncology Ontology

Last uploaded: June 19, 2018
Preferred Name

Vindesine

Synonyms
Definitions

A synthetic derivative of vinblastine, a naturally occurring vinca alkaloid. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C934

definition

A synthetic derivative of vinblastine, a naturally occurring vinca alkaloid. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI04)

isDefinedBy

http://purl.bioontology.org/ontology/NCIT

label

Vindesine

prefixIRI

ncit:C934

prefLabel

Vindesine

seeAlso

EuroCAT Umbrella Protocol for NSCLC

subClassOf

http://purl.bioontology.org/ontology/STY/T121

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C932

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C934 NCIT SAME_URI
http://www.drugbank.ca/drugs/DB00309 FTC LOOM
http://purl.bioontology.org/ontology/MESH/D014751 MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_36373 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_36373 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_36373 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_36373 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_36373 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_36373 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_36373 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_36373 NIFSTD LOOM
http://purl.bioontology.org/ontology/RCD/x01Al RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014751 RH-MESH LOOM
http://purl.jp/bio/4/id/200906079585934757 IOBC LOOM
http://purl.obolibrary.org/obo/OMIT_0015582 OMIT LOOM
http://www.gamuts.net/entity#vindesine GAMUTS LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.436.681.827.830 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.473.402.681.827.830 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/11204 RXNORM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/409198005 SNOMEDCT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C934 NCIT LOOM
http://purl.bioontology.org/ontology/ATC/L01CA03 ATC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000171809 NDFRT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#13002 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0042682 OCHV LOOM
http://purl.obolibrary.org/obo/MESH_D014751 BERO LOOM
http://www.co-ode.org/ontologies/galen#Vindesine GALEN LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017738 PMAPP-PMO LOOM
http://stirdf.jst.go.jp/id/200907054873213216 IOBC LOOM
http://purl.bioontology.org/ontology/VANDF/4025282 VANDF LOOM
http://purl.bioontology.org/ontology/NDDF/003505 NDDF LOOM
https://go.drugbank.com/drugs/DB00309 MDM LOOM
http://purl.obolibrary.org/obo/NCIT_C934 BERO LOOM