Radiology Lexicon

Last uploaded: January 14, 2019
Preferred Name

multiple system atrophy

Synonyms

Shy-Drager disease

Definitions

A syndrome complex composed of three conditions which represent clinical variants of the same disease process: striatonigral degeneration; shy-drager syndrome; and the sporadic form of olivopontocerebellar atrophies. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92) [MeSH]

ID

http://radlex.org/RID/RID5158

Definition

A syndrome complex composed of three conditions which represent clinical variants of the same disease process: striatonigral degeneration; shy-drager syndrome; and the sporadic form of olivopontocerebellar atrophies. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92) [MeSH]

label

RID5158

May_Cause

http://radlex.org/RID/RID35284

Preferred_name

multiple system atrophy

Preferred_name_German

Multiple Systematrophie

prefixIRI

RID5158

Synonym

Shy-Drager disease

multisystem atrophy

UMLS_ID

C0393571

subClassOf

http://radlex.org/RID/RID5125

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