loading...| Preferred Name |
cefoxitin |
|
| Synonyms |
(6R,7S)-4-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 3-[(carbamoyloxy)methyl]-7alpha-methoxy-7beta-[(thiophen-2-yl)acetamido]-3,4-didehydrocepham-4-carboxylic acid Cefoxitin cefoxitinum (6R,7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid CFX Cephoxitin Rephoxitin cefoxitin cefoxitina cefoxitine ceftoxitin |
|
| Definitions |
A semisynthetic cephamycin antibiotic which, in addition to the methoxy group at the 7alpha position, has 2-thienylacetamido and carbamoyloxymethyl side-groups. It is resistant to beta-lactamase. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_209807 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:17923492 Wikipedia:Cefoxitin KEGG:C06887 PMID:18056283 PMID:17387156 Patent:DE2203653 Reaxys:4216947 HMDB:HMDB0015426 PMID:12569987 PMID:8360877 Patent:US4297488 PMID:17043131 PMID:17220412 Beilstein:4216947 LINCS:LSM-5786 Patent:DE2129675 PMID:2083978 PMID:29017833 PMID:18070972 PMID:17178800 PDBeChem:CFX KEGG:D02345 DrugBank:DB01331 PMID:17353248 Drug_Central:550 CAS:35607-66-0 |
|
| formula |
C16H17N3O7S2 |
|
| has role | ||
| has_alternative_id |
CHEBI:471714 CHEBI:41436 CHEBI:658070 CHEBI:3500 |
|
| has_exact_synonym |
(6R,7S)-4-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 3-[(carbamoyloxy)methyl]-7alpha-methoxy-7beta-[(thiophen-2-yl)acetamido]-3,4-didehydrocepham-4-carboxylic acid Cefoxitin |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
cefoxitinum (6R,7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid CFX Cephoxitin Rephoxitin cefoxitin cefoxitina cefoxitine ceftoxitin |
|
| id |
CHEBI:209807 |
|
| in_subset | ||
| inchi |
InChI=1S/C16H17N3O7S2/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22)/t14-,16+/m1/s1 |
|
| inchikey |
WZOZEZRFJCJXNZ-ZBFHGGJFSA-N |
|
| is_conjugate_acid_of | ||
| label |
cefoxitin |
|
| mass |
427.45200 |
|
| monoisotopicmass |
427.05079 |
|
| notation |
CHEBI:209807 |
|
| prefLabel |
cefoxitin |
|
| smiles |
[H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@]2(NC(=O)Cc1cccs1)OC)C(O)=O |
|
| textual definition |
A semisynthetic cephamycin antibiotic which, in addition to the methoxy group at the 7alpha position, has 2-thienylacetamido and carbamoyloxymethyl side-groups. It is resistant to beta-lactamase. |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_23066 http://purl.obolibrary.org/obo/CHEBI_72588 |