Preferred Name

norfloxacin

Synonyms

1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

norfloxacino

norfloxacinum

1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

NFLX

norfloxacin

norfloxacine

1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure

Definitions

A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

ID

http://purl.obolibrary.org/obo/CHEBI_100246

charge

0

database_cross_reference

VSDB:1831

DrugBank:DB01059

Patent:BE863429

Patent:US4292317

HMDB:HMDB0015192

PMID:6234465

PMID:6461606

Gmelin:1576626

PMID:6211142

Reaxys:567897

PMID:3908074

Patent:DE2840910

KEGG:D00210

PMID:6454381

KEGG:C06687

PMID:6224685

Patent:US4146719

Beilstein:567897

LINCS:LSM-5286

CAS:70458-96-7

PMID:3317294

Drug_Central:1967

Wikipedia:Norfloxacin

definition

A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

formula

C16H18FN3O3

has role

http://purl.obolibrary.org/obo/CHEBI_35703

http://purl.obolibrary.org/obo/CHEBI_36047

http://purl.obolibrary.org/obo/CHEBI_78298

http://purl.obolibrary.org/obo/CHEBI_59517

has_alternative_id

CHEBI:7629

has_exact_synonym

1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

has_obo_namespace

chebi_ontology

has_related_synonym

1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

norfloxacino

norfloxacinum

NFLX

norfloxacin

norfloxacine

1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure

id

CHEBI:100246

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)

inchikey

OGJPXUAPXNRGGI-UHFFFAOYSA-N

label

norfloxacin

mass

319.33080

monoisotopicmass

319.13322

notation

CHEBI:100246

prefLabel

norfloxacin

smiles

CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCNCC1

subClassOf

http://purl.obolibrary.org/obo/CHEBI_46848

http://purl.obolibrary.org/obo/CHEBI_87211

http://purl.obolibrary.org/obo/CHEBI_26512

http://purl.obolibrary.org/obo/CHEBI_23765

http://purl.obolibrary.org/obo/CHEBI_86324

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