loading...| Preferred Name |
diclofenac sodium |
|
| Synonyms |
Voltaren |
|
| Definitions |
The sodium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity. Diclofenac sodium is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47984" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47984" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000792632 |
|
| altLabel |
Voltaren GP 45840 2-[(2,6-dichlorophenyl)amino]benzeneacetic acid monosodium salt |
|
| CAS Registry |
15307-79-6 |
|
| cui |
C0700583 C0699958 C2718114 |
|
| DATE FIRST PUBLISHED |
2018-03-15 |
|
| Date last modified |
2018-03-15 |
|
| definition |
The sodium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity. Diclofenac sodium is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47984" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47984" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C47984 |
|
| notation |
CDR0000792632 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
diclofenac sodium |
|
| tui |
T109 T121 |