Preferred Name |
cyclobenzaprine hydrochloride |
|
Synonyms |
Flexeril |
|
Definitions |
A centrally acting muscle relaxant, chemically similar to amitriptyline hydrochloride with antidepressant activity. The exact mechanism of action of cyclobenzaprine hydrochloride has not been fully determined. However, it primarily acts at the brain stem to reduce tonic somatic motor activity, influencing both gamma and alpha motor neurons. This leads to a reduction in muscle spasms. |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000751769 |
|
altLabel |
Flexeril 3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)propyl(dimethyl)ammonium chloride 1-propanamine, 3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride Novo-Cycloprine Flexiban Cycloflex cloben 10,11delta-amitriptyline hydrochloride FR2100873 |
|
CAS Registry |
6202-23-9 |
|
cui |
C4282177 C4282176 C4282174 C0125988 C0728797 C4282175 C1330429 |
|
DATE FIRST PUBLISHED |
2013-08-15 |
|
Date last modified |
2013-08-15 |
|
definition |
A centrally acting muscle relaxant, chemically similar to amitriptyline hydrochloride with antidepressant activity. The exact mechanism of action of cyclobenzaprine hydrochloride has not been fully determined. However, it primarily acts at the brain stem to reduce tonic somatic motor activity, influencing both gamma and alpha motor neurons. This leads to a reduction in muscle spasms. |
|
LT |
TRD |
|
notation |
CDR0000751769 |
|
NSC Code |
169900 173379 78206 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
cyclobenzaprine hydrochloride |
|
tui |
T109 T121 |