Physician Data Query

Last uploaded: August 27, 2019
Preferred Name

ketoprofen

Synonyms

dexketoprofen

Definitions

A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000743614

altLabel

dexketoprofen

Orudis

propionic scid, 2-(3-benzoylphenyl)-

capisten

benzeneacetic Acid, 3-benzoyl-alpha-methyl-

Oruvail

CAS Registry

22071-15-4

cui

C0591927

C0022635

C0772505

C0700190

DATE FIRST PUBLISHED

2012-12-03

Date last modified

2017-02-01

definition

A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

LT

TRD

notation

CDR0000743614

ORIG STY

Drug/agent

prefLabel

ketoprofen

tui

T109

T121

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http://purl.bioontology.org/ontology/MSHFRE/D007660 MSHFRE CUI
http://purl.obolibrary.org/obo/CHEBI_6128 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_6128 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6128 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6128 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_6128 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6128 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6128 NIFSTD LOOM
http://www.semanticweb.org/席婷/ontologies/2019/3/untitled-ontology-62#Ketoprofen PCALION LOOM
http://purl.jp/bio/4/id/200906039199618296 IOBC LOOM
http://www.co-ode.org/ontologies/galen#Ketoprofen GALEN LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/10099000 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SCTSPA/329961001 SCTSPA CUI
http://purl.bioontology.org/ontology/RCD/j2a.. RCD CUI
http://purl.bioontology.org/ontology/RCD/j2a.. RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D007660 RH-MESH LOOM
http://purl.bioontology.org/ontology/UATC/M01AE17 ATC CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.223.701.480 RH-MESH LOOM
http://purl.bioontology.org/ontology/SCTSPA/10099000 SCTSPA CUI
http://purl.bioontology.org/ontology/RXNORM/6142 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/6142 RXNORM LOOM
http://purl.bioontology.org/ontology/NDDF/007781 NDDF CUI
http://sbmi.uth.tmc.edu/ontology/ochv#C0022635 OCHV LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/396018005 SNOMEDCT CUI
http://stirdf.jst.go.jp/id/200907020003429840 IOBC LOOM
http://purl.bioontology.org/ontology/SCTSPA/396018005 SCTSPA CUI
http://purl.bioontology.org/ontology/UATC/M02AA10 ATC CUI
http://purl.bioontology.org/ontology/UATC/M02AA10 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4018064 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4018064 VANDF LOOM
http://www.drugbank.ca/drugs/DB01009 FTC LOOM
http://purl.bioontology.org/ontology/UATC/M01AE03 ATC CUI
http://purl.bioontology.org/ontology/UATC/M01AE03 ATC LOOM
http://purl.bioontology.org/ontology/SNMI/C-603E0 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-603E0 SNMI LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/329961001 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/386832008 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/386832008 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/NDDF/002394 NDDF CUI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47578 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47578 NCIT LOOM
http://purl.bioontology.org/ontology/UATC/M02AA27 ATC CUI
http://purl.bioontology.org/ontology/RXNORM/237162 RXNORM CUI
http://purl.bioontology.org/ontology/RCD/x02mH RCD CUI
http://purl.bioontology.org/ontology/LNC/MTHU007198 LOINC CUI
http://purl.bioontology.org/ontology/LNC/MTHU007198 LOINC LOOM
http://purl.bioontology.org/ontology/SCTSPA/386832008 SCTSPA CUI
http://purl.bioontology.org/ontology/LNC/LP18985-9 LOINC CUI
http://purl.bioontology.org/ontology/LNC/LP18985-9 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000007341 NDFRT CUI
http://purl.bioontology.org/ontology/MESH/C118296 MESH CUI
http://purl.bioontology.org/ontology/MESH/D007660 MESH CUI
http://purl.bioontology.org/ontology/MESH/D007660 MESH CUI
http://purl.bioontology.org/ontology/MESH/D007660 MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7079 OCHV LOOM
http://purl.bioontology.org/ontology/RCD/x02mI RCD CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146405 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146405 NDFRT LOOM
http://scai.fraunhofer.de/AlzheimerOntology#ketoprofen ADO LOOM