Preferred Name |
linezolid |
|
Synonyms |
Zyvox |
|
Definitions |
A synthetic oxazolidinone derivative, linezolid selectively inhibits an early step in bacterial protein synthesis and affects blood pressure through monoamine oxidase inhibition. It is effective against Gram-positive organisms, including methicillin-resistant Staphylococcus aureus strains, coagulase-negative Staphylococci, vancomycin-resistant Enterococci, and penicillin-resistant Streptococcus pneumoniae strains. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29158" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29158" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000735710 |
|
altLabel |
Zyvox |
|
CAS Registry |
165800-03-3 |
|
cui |
C0876226 C0663241 |
|
DATE FIRST PUBLISHED |
2012-06-19 |
|
Date last modified |
2012-06-20 |
|
definition |
A synthetic oxazolidinone derivative, linezolid selectively inhibits an early step in bacterial protein synthesis and affects blood pressure through monoamine oxidase inhibition. It is effective against Gram-positive organisms, including methicillin-resistant Staphylococcus aureus strains, coagulase-negative Staphylococci, vancomycin-resistant Enterococci, and penicillin-resistant Streptococcus pneumoniae strains. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29158" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29158" NCI Thesaurus) |
|
LT |
TRD |
|
NCI ID |
C29158 |
|
notation |
CDR0000735710 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
linezolid |
|
tui |
T109 T121 |