loading...| Preferred Name |
norepinephrine |
|
| Synonyms |
(R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol |
|
| Definitions |
A synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine. Norepinephrine acts directly on the alpha- and beta-adrenergic receptors. Clinically, norepinephrine is used as a peripheral vasoconstrictor that causes constriction of arterial and venous beds via its alpha-adrenergic action. It is also used as a potent inotropic and chronotropic stimulator of the heart mediated through its beta-1 adrenergic action. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C62098" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C62098" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000691834 |
|
| altLabel |
(R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol Noradrenaline Arterenol |
|
| CAS Registry |
51-41-2 |
|
| cui |
C0205860 C0028351 |
|
| DATE FIRST PUBLISHED |
2010-12-22 |
|
| Date last modified |
2017-03-30 |
|
| definition |
A synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine. Norepinephrine acts directly on the alpha- and beta-adrenergic receptors. Clinically, norepinephrine is used as a peripheral vasoconstrictor that causes constriction of arterial and venous beds via its alpha-adrenergic action. It is also used as a potent inotropic and chronotropic stimulator of the heart mediated through its beta-1 adrenergic action. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C62098" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C62098" NCI Thesaurus) |
|
| NCI ID |
C62098 |
|
| notation |
CDR0000691834 |
|
| NSC Code |
294898 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
norepinephrine |
|
| tui |
T125 T109 T121 |