Physician Data Query

Last uploaded: November 18, 2019
Preferred Name

desflurane

Synonyms

Ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro-,(+-)-

Definitions

A fluorinated ether with general anesthetic and muscle relaxant activities. Although the exact mechanism of action has not been established, desflurane, administered by inhalation, appears to act on the lipid matirx of the neuronal membrane, resulting in disruption of neuronal transmission in the brain. This agent may also enhance the synaptic activity of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47472" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47472" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000574264

altLabel

Ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro-,(+-)-

Suprane

I 653

CAS Registry

57041-67-5

cui

C0063252

C0592148

C0950711

DATE FIRST PUBLISHED

2007-10-24

Date last modified

2007-10-24

definition

A fluorinated ether with general anesthetic and muscle relaxant activities. Although the exact mechanism of action has not been established, desflurane, administered by inhalation, appears to act on the lipid matirx of the neuronal membrane, resulting in disruption of neuronal transmission in the brain. This agent may also enhance the synaptic activity of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47472" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47472" NCI Thesaurus)

LT

TRD

NCI ID

C47472

notation

CDR0000574264

ORIG STY

Drug/agent

prefLabel

desflurane

tui

T109

T121

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http://phenomebrowser.net/ontologies/mesh/mesh.owl#C053562 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47472 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47472 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47472 NCIT LOOM
http://purl.bioontology.org/ontology/NDDF/004114 NDDF CUI
http://purl.bioontology.org/ontology/MSHFRE/D000077335 MSHFRE CUI
http://purl.bioontology.org/ontology/MSHFRE/D000077335 MSHFRE CUI
http://purl.obolibrary.org/obo/DRON_00013063 DRON LOOM
http://purl.obolibrary.org/obo/DRON_00013063 DRON LOOM
http://purl.obolibrary.org/obo/DRON_00013063 DRON LOOM
http://purl.bioontology.org/ontology/RCD/o28.. RCD CUI
http://purl.bioontology.org/ontology/RCD/o28.. RCD LOOM
http://purl.bioontology.org/ontology/MESH/D000077335 MESH CUI
http://purl.bioontology.org/ontology/MESH/D000077335 MESH CUI
http://purl.bioontology.org/ontology/MESH/D000077335 MESH CUI
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http://purl.bioontology.org/ontology/LNC/MTHU050116 LOINC CUI
http://purl.bioontology.org/ontology/LNC/MTHU050116 LOINC LOOM
http://purl.bioontology.org/ontology/SCTSPA/108393001 SCTSPA CUI
http://purl.obolibrary.org/obo/CHEBI_4445 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4445 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4445 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4445 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4445 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4445 NIFSTD LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000007342 NDFRT CUI
http://purl.bioontology.org/ontology/LNC/LP101882-1 LOINC CUI
http://purl.bioontology.org/ontology/LNC/LP101882-1 LOINC LOOM
http://www.drugbank.ca/drugs/DB01189 FTC LOOM
http://purl.bioontology.org/ontology/VANDF/4020649 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4020649 VANDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0063252 OCHV LOOM
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http://purl.bioontology.org/ontology/UATC/N01AB07 ATC CUI
http://purl.bioontology.org/ontology/UATC/N01AB07 ATC LOOM
http://www.co-ode.org/ontologies/galen#Desflurane GALEN LOOM
http://purl.bioontology.org/ontology/RXNORM/27340 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/27340 RXNORM LOOM
http://purl.bioontology.org/ontology/SCTSPA/386841003 SCTSPA CUI
http://purl.bioontology.org/ontology/RXNORM/152394 RXNORM CUI