Physician Data Query

Last uploaded: November 18, 2019
Preferred Name

levonorgestrel

Synonyms

(17Alpha)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one

Definitions

The levorotatory form of norgestrel and synthetic progestogen with progestational and androgenic activity. Levonorgestrel binds to the progesterone receptor in the nucleus of target cells, thereby stimulating the resulting hormone-receptor complex, initiating transcription, and increasing the synthesis of certain proteins. This results in a suppression of luteinizing hormone (LH) activity and an inhibition of ovulation, as well as an alteration in the cervical mucus and endometrium. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47585" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47585" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000534399

altLabel

(17Alpha)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one

18-Methylnorethisterone

D-(-)-Norgestrel

Norplant

Plan B

13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one

CAS Registry

797-63-7

cui

C0876128

C0023566

C1145675

DATE FIRST PUBLISHED

2007-02-22

definition

The levorotatory form of norgestrel and synthetic progestogen with progestational and androgenic activity. Levonorgestrel binds to the progesterone receptor in the nucleus of target cells, thereby stimulating the resulting hormone-receptor complex, initiating transcription, and increasing the synthesis of certain proteins. This results in a suppression of luteinizing hormone (LH) activity and an inhibition of ovulation, as well as an alteration in the cervical mucus and endometrium. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C47585" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C47585" NCI Thesaurus)

LT

TRD

NCI ID

C47585

notation

CDR0000534399

ORIG STY

Drug/agent

prefLabel

levonorgestrel

tui

T125

T109

T121

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http://sbmi.uth.tmc.edu/ontology/ochv#C0023566 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4018027 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4018027 VANDF LOOM
http://purl.obolibrary.org/obo/CHEBI_6443 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_6443 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_6443 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6443 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6443 NIFSTD LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/126109000 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/126109000 SNOMEDCT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47585 NCIT LOOM
http://www.drugbank.ca/drugs/DB00367 FTC LOOM
http://purl.bioontology.org/ontology/SCTSPA/126109000 SCTSPA CUI
http://purl.bioontology.org/ontology/UATC/G03AC03 ATC CUI
http://purl.bioontology.org/ontology/UATC/G03AC03 ATC LOOM
http://purl.bioontology.org/ontology/RXNORM/6373 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/6373 RXNORM LOOM
http://purl.bioontology.org/ontology/CSP/4007-0091 CRISP CUI
http://purl.bioontology.org/ontology/CSP/4007-0091 CRISP CUI
http://purl.bioontology.org/ontology/CSP/4007-0091 CRISP LOOM
http://purl.bioontology.org/ontology/UATC/G03AD01 ATC CUI
http://purl.bioontology.org/ontology/UATC/G03AD01 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7376 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146370 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146370 NDFRT LOOM
http://purl.bioontology.org/ontology/MSHFRE/D016912 MSHFRE CUI
http://purl.bioontology.org/ontology/CSP/0962-5821 CRISP CUI
http://purl.jp/bio/4/id/200906099786006379 IOBC LOOM
http://purl.bioontology.org/ontology/SCTSPA/109032009 SCTSPA CUI
http://purl.bioontology.org/ontology/NDFRT/N0000007395 NDFRT CUI
http://purl.bioontology.org/ontology/MESH/D016912 MESH CUI
http://purl.bioontology.org/ontology/MESH/D016912 MESH CUI
http://purl.bioontology.org/ontology/MESH/D016912 MESH CUI
http://purl.bioontology.org/ontology/MESH/D016912 MESH LOOM
http://purl.bioontology.org/ontology/RCD/x02lL RCD CUI
http://www.co-ode.org/ontologies/galen#Levonorgestrel GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.808.668.651.693.762.450 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907099159023954 IOBC LOOM
http://www.semanticweb.org/ontologies/epo.owl#Levonorgestrel EPO LOOM
http://purl.bioontology.org/ontology/NDDF/001304 NDDF CUI
http://purl.bioontology.org/ontology/NDDF/001304 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D016912 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/x02MF RCD CUI
http://purl.bioontology.org/ontology/SNMI/C-C2058 SNMI CUI
http://purl.bioontology.org/ontology/SNOMEDCT/109032009 SNOMEDCT CUI
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004734 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0004734 DMTO LOOM