Physician Data Query

Last uploaded: November 18, 2019
Preferred Name

cobalamin

Synonyms

cobalamin (1+)

Definitions

An essential nutrient and natural water-soluble vitamin of the B-complex family that must combine with an intrinsic factor for absorption by the intestine, Vitamin B12 (cyanocobalamin) is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C939" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C939" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000530928

altLabel

cobalamin (1+)

vitamin-B12

vit B12

vitamin B-12

B12 vitamin

vitamin B12

CAS Registry

13408-78-1

cui

C0042845

DATE FIRST PUBLISHED

2007-01-19

Date last modified

2017-12-15

definition

An essential nutrient and natural water-soluble vitamin of the B-complex family that must combine with an intrinsic factor for absorption by the intestine, Vitamin B12 (cyanocobalamin) is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C939" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C939" NCI Thesaurus)

NCI ID

C939

notation

CDR0000530928

ORIG STY

Drug/agent

prefLabel

cobalamin

tui

T109

T127

T121

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http://purl.bioontology.org/ontology/SCTSPA/419382002 SCTSPA CUI
http://purl.bioontology.org/ontology/SNOMEDCT/419382002 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNMI/F-BB360 SNMI CUI
http://purl.bioontology.org/ontology/SNOMEDCT/30010009 SNOMEDCT CUI
http://purl.bioontology.org/ontology/LNC/LP15262-6 LOINC CUI
http://purl.bioontology.org/ontology/LNC/LP31689-0 LOINC CUI
http://purl.bioontology.org/ontology/UATC/B03BA01 ATC CUI
http://purl.bioontology.org/ontology/RCD/i32.. RCD CUI
http://purl.bioontology.org/ontology/SNMI/C-A4472 SNMI CUI
http://purl.bioontology.org/ontology/CSP/3147-6039 CRISP CUI
http://purl.bioontology.org/ontology/LNC/MTHU005166 LOINC LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_30411 ONSTR LOOM
http://purl.bioontology.org/ontology/NDDF/001043 NDDF CUI
http://purl.bioontology.org/ontology/MESH/D014805 MESH CUI
http://purl.bioontology.org/ontology/RCD/x03iX RCD CUI
http://purl.bioontology.org/ontology/SCTSPA/30010009 SCTSPA CUI
http://purl.bioontology.org/ontology/RCD/X80RX RCD CUI
http://www.co-ode.org/ontologies/galen#Cobalamin GALEN LOOM
http://purl.jp/bio/10/gmo/GMO_001034 GMO LOOM
http://purl.bioontology.org/ontology/CSP/3144-1115 CRISP CUI
http://purl.bioontology.org/ontology/VANDF/4017441 VANDF CUI
http://purl.bioontology.org/ontology/RXNORM/11248 RXNORM CUI
http://sbmi.uth.tmc.edu/ontology/ochv#15822 OCHV LOOM
http://purl.bioontology.org/ontology/RCD/Xa9qL RCD LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C939 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C939 NCIT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0086024 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4017907 VANDF LOOM
http://purl.bioontology.org/ontology/MSHFRE/D014805 MSHFRE CUI
http://purl.jp/bio/4/id/200906025628789095 IOBC LOOM
http://purl.bioontology.org/ontology/CSP/3144-2999 CRISP LOOM
http://purl.bioontology.org/ontology/LNC/LP268966-1 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146258 NDFRT LOOM
http://purl.bioontology.org/ontology/LNC/LP32549-5 LOINC CUI
http://purl.bioontology.org/ontology/SNMI/C-A4470 SNMI CUI
http://purl.bioontology.org/ontology/SNOMEDCT/304111003 SNOMEDCT LOOM