Physician Data Query

Last uploaded: July 6, 2018
Preferred Name

Glutathione Disulfide

Synonyms

GSH

Definitions

A tripeptide comprised of three amino acids (cysteine, glutamic acid, and glycine) present in most mammalian tissue. Glutathione acts as an antioxidant, a free radical scavenger and as a detoxifying agent. Glutathione is also important as a cofactor for the enzyme glutathione peroxidase, in the uptake of amino acids and participates in leukotriene synthesis. Under the influence of glutathione S-transferase, glutathione can react with a number of harmful products, such as halides, epoxides and free radicals, to form harmless inactive products. In erythrocytes, these reactions prevent oxidative damage by reduction of methemoglobin and peroxides. Glutathione is also involved in the formation and maintenance of disulfide bonds in proteins and in transport of amino acids across cell membranes. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=486929&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=486929&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C523" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000486929

altLabel

GSH

Glutathione

N-(N-L-gamma-glutamyl-L-cysteinyl)glycine

CAS Registry

70-18-8

cui

C0061516

C0017817

DATE FIRST PUBLISHED

2006-06-02

definition

A tripeptide comprised of three amino acids (cysteine, glutamic acid, and glycine) present in most mammalian tissue. Glutathione acts as an antioxidant, a free radical scavenger and as a detoxifying agent. Glutathione is also important as a cofactor for the enzyme glutathione peroxidase, in the uptake of amino acids and participates in leukotriene synthesis. Under the influence of glutathione S-transferase, glutathione can react with a number of harmful products, such as halides, epoxides and free radicals, to form harmless inactive products. In erythrocytes, these reactions prevent oxidative damage by reduction of methemoglobin and peroxides. Glutathione is also involved in the formation and maintenance of disulfide bonds in proteins and in transport of amino acids across cell membranes. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=486929&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=486929&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C523" NCI Thesaurus)

NCI ID

C523

notation

CDR0000486929

NSC Code

400639

ORIG STY

Drug/agent

prefLabel

Glutathione Disulfide

tui

T116

T121

T123

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http://purl.bioontology.org/ontology/RXNORM/25953 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/25953 RXNORM LOOM
http://purl.bioontology.org/ontology/LNC/LP71481-3 LOINC CUI
http://purl.bioontology.org/ontology/CSP/2237-5409 CRISP CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D019803 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000170317 NDFRT CUI
http://purl.bioontology.org/ontology/SCTSPA/55477000 SCTSPA CUI
http://purl.bioontology.org/ontology/RXNORM/4890 RXNORM CUI
http://purl.bioontology.org/ontology/SNOMEDCT/6817006 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/423272009 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SCTSPA/423272009 SCTSPA CUI
http://purl.bioontology.org/ontology/LNC/LP15615-5 LOINC CUI
http://purl.bioontology.org/ontology/MSHFRE/D019803 MSHFRE CUI
http://purl.bioontology.org/ontology/MESH/D019803 MESH CUI
http://purl.bioontology.org/ontology/MESH/D019803 MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/55477000 SNOMEDCT CUI
http://purl.bioontology.org/ontology/NDDF/003447 NDDF CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148266 NDFRT CUI
http://purl.bioontology.org/ontology/VANDF/4020562 VANDF CUI
http://purl.bioontology.org/ontology/LNC/MTHU006265 LOINC CUI
http://purl.bioontology.org/ontology/LNC/LP15617-1 LOINC CUI
http://purl.obolibrary.org/obo/CHEBI_17858 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
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http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
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http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_17858 GO-PLUS LOOM
http://purl.bioontology.org/ontology/MSHFRE/D005978 MSHFRE CUI
http://purl.bioontology.org/ontology/NDDF/005967 NDDF CUI
http://purl.bioontology.org/ontology/NDDF/005967 NDDF LOOM
http://purl.bioontology.org/ontology/SCTSPA/6817006 SCTSPA CUI
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.456.448.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/F-61520 SNMI CUI
http://purl.bioontology.org/ontology/NDFRT/N0000006503 NDFRT CUI
http://purl.bioontology.org/ontology/MESH/D005978 MESH CUI
http://purl.bioontology.org/ontology/UATC/V03AB32 ATC CUI
http://purl.bioontology.org/ontology/LNC/MTHU011522 LOINC CUI
http://purl.bioontology.org/ontology/SNMI/F-61530 SNMI CUI