Preferred Name |
glycopeptide antibiotic |
|
Synonyms |
|
|
Definitions |
One of a class of antibiotics originally isolated from plant and soil bacteria with structures containing either a glycosylated cyclic or polycyclic nonribosomal peptide. These antibiotics inhibit the cell wall structure of susceptible organisms (principally Gram-positive cocci) by inhibiting peptidoglycan synthesis.First-generation glycopeptide antibiotics include vancomycin, teicoplanin, and ramoplanin; second-generation semi-synthetic glycopeptide antibiotics include oritavancin, dalbavancin, and telavancin. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C61101" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61101" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000468927 |
|
cui |
C0162724 |
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DATE FIRST PUBLISHED |
2006-02-21 |
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Date last modified |
2006-07-18 |
|
definition |
One of a class of antibiotics originally isolated from plant and soil bacteria with structures containing either a glycosylated cyclic or polycyclic nonribosomal peptide. These antibiotics inhibit the cell wall structure of susceptible organisms (principally Gram-positive cocci) by inhibiting peptidoglycan synthesis.First-generation glycopeptide antibiotics include vancomycin, teicoplanin, and ramoplanin; second-generation semi-synthetic glycopeptide antibiotics include oritavancin, dalbavancin, and telavancin. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C61101" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61101" NCI Thesaurus) |
|
NCI ID |
C61101 |
|
notation |
CDR0000468927 |
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ORIG STY |
Drug/agent |
|
prefLabel |
glycopeptide antibiotic |
|
tui |
T195 T116 |