Physician Data Query

Last uploaded: January 31, 2024
Preferred Name

glycopeptide antibiotic

Synonyms
Definitions

One of a class of antibiotics originally isolated from plant and soil bacteria with structures containing either a glycosylated cyclic or polycyclic nonribosomal peptide. These antibiotics inhibit the cell wall structure of susceptible organisms (principally Gram-positive cocci) by inhibiting peptidoglycan synthesis.First-generation glycopeptide antibiotics include vancomycin, teicoplanin, and ramoplanin; second-generation semi-synthetic glycopeptide antibiotics include oritavancin, dalbavancin, and telavancin. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C61101" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61101" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000468927

cui

C0162724

DATE FIRST PUBLISHED

2006-02-21

Date last modified

2006-07-18

definition

One of a class of antibiotics originally isolated from plant and soil bacteria with structures containing either a glycosylated cyclic or polycyclic nonribosomal peptide. These antibiotics inhibit the cell wall structure of susceptible organisms (principally Gram-positive cocci) by inhibiting peptidoglycan synthesis.First-generation glycopeptide antibiotics include vancomycin, teicoplanin, and ramoplanin; second-generation semi-synthetic glycopeptide antibiotics include oritavancin, dalbavancin, and telavancin. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C61101" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61101" NCI Thesaurus)

NCI ID

C61101

notation

CDR0000468927

ORIG STY

Drug/agent

prefLabel

glycopeptide antibiotic

tui

T195

T116

Delete Subject Author Type Created
No notes to display