Physician Data Query

Last uploaded: August 27, 2019
Preferred Name

etoricoxib

Synonyms

MK-0663

Definitions

A synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic ,and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C52188" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C52188" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000462092

altLabel

MK-0663

L-791456

5-Chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl) Pyridine

Arcoxia

cui

C0972314

C1097007

C1530229

C1130504

DATE FIRST PUBLISHED

2006-01-25

Date last modified

2006-08-02

definition

A synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic ,and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C52188" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C52188" NCI Thesaurus)

LT

TRD

NCI ID

C52188

notation

CDR0000462092

ORIG STY

Drug/agent

prefLabel

etoricoxib

tui

T109

T121

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http://purl.bioontology.org/ontology/SNOMEDCT/409134009 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/409134009 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/SCTSPA/409134009 SCTSPA CUI
http://sbmi.uth.tmc.edu/ontology/ochv#C0972314 OCHV LOOM
http://purl.bioontology.org/ontology/SCTSPA/395292007 SCTSPA CUI
http://purl.bioontology.org/ontology/UATC/M01AH05 ATC CUI
http://purl.bioontology.org/ontology/UATC/M01AH05 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D000077613 MESH CUI
http://purl.bioontology.org/ontology/MESH/D000077613 MESH CUI
http://purl.bioontology.org/ontology/MESH/D000077613 MESH CUI
http://purl.bioontology.org/ontology/MESH/D000077613 MESH CUI
http://purl.bioontology.org/ontology/MESH/D000077613 MESH LOOM
http://www.drugbank.ca/drugs/DB01628 FTC LOOM
http://purl.obolibrary.org/obo/CHEBI_6339 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_6339 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6339 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_6339 CHEBI LOOM
http://purl.bioontology.org/ontology/CSP/5005-0005 CRISP CUI
http://purl.bioontology.org/ontology/SNOMEDCT/395292007 SNOMEDCT CUI
http://sbmi.uth.tmc.edu/ontology/ochv#53645 OCHV LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C52188 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C52188 NCIT LOOM
http://purl.obolibrary.org/obo/DRON_00018671 DRON LOOM
http://purl.obolibrary.org/obo/DRON_00018671 DRON LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C422649 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/009633 NDDF CUI
http://purl.bioontology.org/ontology/NDDF/009633 NDDF LOOM
http://purl.bioontology.org/ontology/RXNORM/307296 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/307296 RXNORM LOOM
http://purl.bioontology.org/ontology/MSHFRE/D000077613 MSHFRE CUI
http://purl.bioontology.org/ontology/MSHFRE/D000077613 MSHFRE CUI
http://purl.bioontology.org/ontology/MSHFRE/D000077613 MSHFRE CUI