Preferred Name |
sildenafil citrate |
|
Synonyms |
Viagra |
|
Definitions |
The citrate salt of a pyrazolopyrimidinone derivative structurally related to zaprinast. Sildenafil selectively inhibits cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase, resulting in vasodilation in the corpus cavernosum of the penis and penile erection. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C26670" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C26670" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000269137 |
|
altLabel |
Viagra |
|
cui |
C0724693 C0663448 |
|
DATE FIRST PUBLISHED |
2002-11-24 |
|
Date last modified |
2007-02-08 |
|
definition |
The citrate salt of a pyrazolopyrimidinone derivative structurally related to zaprinast. Sildenafil selectively inhibits cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase, resulting in vasodilation in the corpus cavernosum of the penis and penile erection. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C26670" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C26670" NCI Thesaurus) |
|
LT |
TRD |
|
NCI ID |
C26670 |
|
notation |
CDR0000269137 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
sildenafil citrate |
|
tui |
T109 T121 |