Physician Data Query

Last uploaded: August 27, 2019
Preferred Name

prednisolone

Synonyms

Pred-Clysma

Definitions

A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C769" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C769" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000043296

altLabel

Pred-Clysma

Di-Adreson-F

Hydeltra

Opredsone

Dontisolon D

Delta-Cortef

Decortin H

Frisolona

Deltidrosol

Panafcortelone

Cortisolone

Prednicortelone

1,2-dehydrohydrocortisone

Kuhlprednon

Hostacortin H

Lepi-Cortinolo

Delta-Diona

Predni-Helvacort

delta1-dehydro-hydrocortisone

Deltasolone

(11beta)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione

Adnisolone

Dhasolone

Delta- Cortef

Deltacortril

deltahydrocortisone

Prelone

Decaprednil

Klismacort

delta(1)hydrocortisone

Fisopred

Prenilone

Delta-Phoricol

Meti-derm

Precortisyl

Dacortin H

Longiprednil

Estilsona

Aprednislon

Hydeltrasol

Capsoid

Gupisone

Predeltilone

Meticortelone

Lenisolone

Linola-H N

metacortandralone

Linola-H-Fett N

Cortalone

PRDL

Predni-Coelin

CAS Registry

50-24-8

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000441233

http://purl.bioontology.org/ontology/PDQ/CDR0000038286

http://purl.bioontology.org/ontology/PDQ/CDR0000041875

http://purl.bioontology.org/ontology/PDQ/CDR0000041272

http://purl.bioontology.org/ontology/PDQ/CDR0000043218

http://purl.bioontology.org/ontology/PDQ/CDR0000042077

http://purl.bioontology.org/ontology/PDQ/CDR0000041909

http://purl.bioontology.org/ontology/PDQ/CDR0000041434

http://purl.bioontology.org/ontology/PDQ/CDR0000041034

http://purl.bioontology.org/ontology/PDQ/CDR0000040328

http://purl.bioontology.org/ontology/PDQ/CDR0000041930

http://purl.bioontology.org/ontology/PDQ/CDR0000039402

http://purl.bioontology.org/ontology/PDQ/CDR0000043396

http://purl.bioontology.org/ontology/PDQ/CDR0000315770

http://purl.bioontology.org/ontology/PDQ/CDR0000043123

http://purl.bioontology.org/ontology/PDQ/CDR0000042037

http://purl.bioontology.org/ontology/PDQ/CDR0000041118

http://purl.bioontology.org/ontology/PDQ/CDR0000038285

http://purl.bioontology.org/ontology/PDQ/CDR0000038308

http://purl.bioontology.org/ontology/PDQ/CDR0000357354

http://purl.bioontology.org/ontology/PDQ/CDR0000038574

http://purl.bioontology.org/ontology/PDQ/CDR0000041933

http://purl.bioontology.org/ontology/PDQ/CDR0000041031

http://purl.bioontology.org/ontology/PDQ/CDR0000043392

http://purl.bioontology.org/ontology/PDQ/CDR0000041444

http://purl.bioontology.org/ontology/PDQ/CDR0000042661

http://purl.bioontology.org/ontology/PDQ/CDR0000038288

http://purl.bioontology.org/ontology/PDQ/CDR0000038292

http://purl.bioontology.org/ontology/PDQ/CDR0000043135

http://purl.bioontology.org/ontology/PDQ/CDR0000315772

http://purl.bioontology.org/ontology/PDQ/CDR0000042427

http://purl.bioontology.org/ontology/PDQ/CDR0000038309

http://purl.bioontology.org/ontology/PDQ/CDR0000041932

http://purl.bioontology.org/ontology/PDQ/CDR0000038307

http://purl.bioontology.org/ontology/PDQ/CDR0000355815

http://purl.bioontology.org/ontology/PDQ/CDR0000041270

http://purl.bioontology.org/ontology/PDQ/CDR0000042038

http://purl.bioontology.org/ontology/PDQ/CDR0000043125

http://purl.bioontology.org/ontology/PDQ/CDR0000038287

http://purl.bioontology.org/ontology/PDQ/CDR0000040416

http://purl.bioontology.org/ontology/PDQ/CDR0000038284

http://purl.bioontology.org/ontology/PDQ/CDR0000043245

http://purl.bioontology.org/ontology/PDQ/CDR0000038442

http://purl.bioontology.org/ontology/PDQ/CDR0000038291

http://purl.bioontology.org/ontology/PDQ/CDR0000042428

http://purl.bioontology.org/ontology/PDQ/CDR0000039589

http://purl.bioontology.org/ontology/PDQ/CDR0000042413

http://purl.bioontology.org/ontology/PDQ/CDR0000039529

http://purl.bioontology.org/ontology/PDQ/CDR0000039533

http://purl.bioontology.org/ontology/PDQ/CDR0000041363

http://purl.bioontology.org/ontology/PDQ/CDR0000041931

http://purl.bioontology.org/ontology/PDQ/CDR0000040353

http://purl.bioontology.org/ontology/PDQ/CDR0000040953

http://purl.bioontology.org/ontology/PDQ/CDR0000040455

http://purl.bioontology.org/ontology/PDQ/CDR0000038310

http://purl.bioontology.org/ontology/PDQ/CDR0000043405

http://purl.bioontology.org/ontology/PDQ/CDR0000037980

http://purl.bioontology.org/ontology/PDQ/CDR0000039523

cui

C1514315

C0699537

C1514331

C1514339

C1514332

C1514327

C1514335

C1514320

C1514316

C1514324

C1514340

C0701477

C1514317

C1514341

C1514333

C1514310

C0032950

C1514312

C1514319

C1514336

C0702183

C1514329

C0699535

C1514338

C1514314

C0591991

C1514309

C1514325

C1514328

C0699539

C1514321

C1514323

C1514334

C1514311

C0722747

C1514342

C1514313

C1514318

C1514326

C1514322

C1514330

C1514337

C0699536

C0591333

Date last modified

2010-06-09

definition

A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C769" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C769" NCI Thesaurus)

IND Code

2537

Legacy PDQ ID

781

LT

TRD

NCI ID

C769

notation

CDR0000043296

NSC Code

9900

ORIG STY

Drug/agent

prefLabel

prednisolone

tui

T109

T121

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http://purl.obolibrary.org/obo/CHEBI_8378 DRON LOOM
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http://purl.obolibrary.org/obo/CHEBI_8378 CHEBI LOOM
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