Preferred Name |
sodium salicylate |
|
Synonyms |
salicylate, sodium |
|
Definitions |
The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C834" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C834" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000043094 |
|
altLabel |
salicylate, sodium benzoic acid, 2-hydroxy-, monosodium salt |
|
CAS Registry |
54-21-7 |
|
cui |
C0037549 |
|
Date last modified |
2017-12-12 |
|
definition |
The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C834" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C834" NCI Thesaurus) |
|
Legacy PDQ ID |
7480 |
|
NCI ID |
C834 |
|
notation |
CDR0000043094 |
|
NSC Code |
202167 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
sodium salicylate |
|
tui |
T109 T121 |