loading...| Preferred Name |
diethylstilbestrol |
|
| Synonyms |
diethylstilbestrolum |
|
| Definitions |
DES; the acronym for diethylstilbestrol, a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, DES inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C433" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C433" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000043081 |
|
| altLabel |
diethylstilbestrolum DES Sexocretin Apstil Estrobene Fonatol Stilboestroform Acnestrol Domestrol Oestromensyl Stilboestrol Boestrol Deladumone Makarol Sibol Oestromon Oestrogenine Serral Microest Estrosyn Estromenin Bufon Synthoestrin Synestrin Neo-Oestronol I Palestrol Antigestil alpha,alpha'-diethylstilbenediol Grafestrol diethylstilbestrol dipropionate Vagestrol Stilbetin stilboestrol dipropionate Oestromenin Diastyl Stilbestrol Stilboefral trans-bis-(hydroxy-4-phenyl)-3,4 hexene-3 Distilbene Stilkap Milestrol 3,4-bis(p-hydroxyphenyl)-3-hexene 4,4'-dihydroxy-alpha,beta-diethylstilbene Sinestrol Cyren A Estrogenine (E)-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol |
|
| CAS Registry |
56-53-1 |
|
| Component of | ||
| cui |
C1511925 C1511931 C1511918 C1511906 C3537266 C1511917 C1831606 C1511932 C1511926 C1511928 C1511923 C1511916 C1511910 C0699331 C1511929 C1511911 C1511912 C1511914 C1511908 C1511909 C0699332 C1511927 C1511922 C1511913 C1511930 C1511919 C1511907 C1511920 C0057300 C0699333 C0057965 C0591106 C0699329 C5441701 C0012203 C1511924 C1511915 C1511921 |
|
| Date last modified |
2010-06-09 |
|
| definition |
DES; the acronym for diethylstilbestrol, a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, DES inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C433" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C433" NCI Thesaurus) |
|
| IND Code |
5019 |
|
| Legacy PDQ ID |
745 |
|
| LT |
TRD |
|
| NCI ID |
C433 |
|
| notation |
CDR0000043081 |
|
| NSC Code |
3070 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
diethylstilbestrol |
|
| tui |
T125 T109 T131 T121 |