loading...| Preferred Name |
ofloxacin |
|
| Synonyms |
|
|
| Definitions |
A fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C712" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C712" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042865 |
|
| CAS Registry |
82419-36-1 |
|
| cui |
C0028902 |
|
| Date last modified |
2006-09-07 |
|
| definition |
A fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C712" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C712" NCI Thesaurus) |
|
| Legacy PDQ ID |
6675 |
|
| NCI ID |
C712 |
|
| notation |
CDR0000042865 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
ofloxacin |
|
| tui |
T109 T195 |