loading...| Preferred Name |
indinavir sulfate |
|
| Synonyms |
IDV |
|
| Definitions |
A synthetic antiviral agent. Indinavir selectively binds to the active site of human immunodeficiency virus (HIV) protease and inhibits its activity, preventing the protease-mediated cleavage of gag-pol viral polyproteins; as a result immature, noninfectious virions are produced. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1662" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1662" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042594 |
|
| altLabel |
IDV Crixivan |
|
| Component of | ||
| cui |
C0701105 C0376637 C0700483 |
|
| Date last modified |
2008-04-09 |
|
| definition |
A synthetic antiviral agent. Indinavir selectively binds to the active site of human immunodeficiency virus (HIV) protease and inhibits its activity, preventing the protease-mediated cleavage of gag-pol viral polyproteins; as a result immature, noninfectious virions are produced. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1662" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1662" NCI Thesaurus) |
|
| Legacy PDQ ID |
6298 |
|
| LT |
TRD |
|
| NCI ID |
C1662 |
|
| notation |
CDR0000042594 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
indinavir sulfate |
|
| tui |
T109 T121 |