Preferred Name |
doxycycline calcium |
|
Synonyms |
Vibramycin |
|
Definitions |
The calcium salt form of doxycycline exhibiting antimicrobial activity. Doxycycline blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. In addition, this agent has exhibited inhibition of collagenase activity. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29008" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29008" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042494 |
|
altLabel |
Vibramycin |
|
CAS Registry |
94088-85-4 |
|
cui |
C0282155 C0699957 |
|
Date last modified |
2017-12-11 |
|
definition |
The calcium salt form of doxycycline exhibiting antimicrobial activity. Doxycycline blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. In addition, this agent has exhibited inhibition of collagenase activity. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C29008" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29008" NCI Thesaurus) |
|
Legacy PDQ ID |
6054 |
|
LT |
TRD |
|
NCI ID |
C29008 |
|
notation |
CDR0000042494 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
doxycycline calcium |
|
tui |
T109 T195 |