Preferred Name |
glutamine |
|
Synonyms |
NutreStore |
|
Definitions |
A nonessential amino acid. Glutamine can donate the ammonia on its side chain to the formation of urea (for eventual excretion by the kidneys) and to purines (necessary for the synthesis of nucleic acids). Glutamic acid-to-glutamine conversion, in which an ammonia group is added to glutamic acid (catalyzed by glutamine synthase), is of central importance in the regulation of toxic levels of ammonia in the body. This agent is a substrate for the production of both excitatory and inhibitory neurotransmitters (glutamate and GABA) and is also an important source of energy for the nervous system. Glutamine may become a conditionally essential amino acid during certain catabolic states. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C522" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C522" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042298 |
|
altLabel |
NutreStore Sympt-X glutamic acid 5-amide Glutapak-10 Enterex Glutapak-10 GlutaSolve L-glutamine 2-aminoglutaramic acid Sympt-X G.I. levoglutamide Q. Levoglutamide Memoril Glutaven Glutasolve Resource Gln Glutacerebro |
|
CAS Registry |
56-85-9 |
|
cui |
C4087033 C1512215 C1512214 C2683448 C1658301 C0017797 C1512216 C4053550 C1880990 C4732953 |
|
Date last modified |
2016-03-23 |
|
definition |
A nonessential amino acid. Glutamine can donate the ammonia on its side chain to the formation of urea (for eventual excretion by the kidneys) and to purines (necessary for the synthesis of nucleic acids). Glutamic acid-to-glutamine conversion, in which an ammonia group is added to glutamic acid (catalyzed by glutamine synthase), is of central importance in the regulation of toxic levels of ammonia in the body. This agent is a substrate for the production of both excitatory and inhibitory neurotransmitters (glutamate and GABA) and is also an important source of energy for the nervous system. Glutamine may become a conditionally essential amino acid during certain catabolic states. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C522" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C522" NCI Thesaurus) |
|
Legacy PDQ ID |
5545 |
|
LT |
TRD |
|
NCI ID |
C522 |
|
notation |
CDR0000042298 |
|
NSC Code |
27421 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
glutamine |
|
tui |
T116 T123 T168 T121 |