loading...| Preferred Name |
exemestane |
|
| Synonyms |
FCE 24304 |
|
| Definitions |
A synthetic androgen analogue. Exemestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1097" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1097" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042297 |
|
| altLabel |
FCE 24304 Aromasin 6-Methyleneandrosta-1,4-diene-3,17-dione PNU 155971 FCE-24304 |
|
| CAS Registry |
107868-30-4 |
|
| Component of |
http://purl.bioontology.org/ontology/PDQ/CDR0000038197 http://purl.bioontology.org/ontology/PDQ/CDR0000037842 http://purl.bioontology.org/ontology/PDQ/CDR0000322248 http://purl.bioontology.org/ontology/PDQ/CDR0000038562 |
|
| cui |
C0851344 C1328679 C0876723 C0060116 |
|
| Date last modified |
2006-05-08 |
|
| definition |
A synthetic androgen analogue. Exemestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1097" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1097" NCI Thesaurus) |
|
| Legacy PDQ ID |
5544 |
|
| LT |
TRD |
|
| NCI ID |
C1097 |
|
| notation |
CDR0000042297 |
|
| NSC Code |
713563 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
exemestane |
|
| tui |
T109 T121 |