Physician Data Query

Last uploaded: January 31, 2024
Preferred Name

recombinant human stem cell factor

Synonyms

steel factor

Definitions

A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant human stem cell factor (rhSCF) binds to the receptor tyrosine kinase c-kit, which may stimulate the growth of peripheral blood progenitor cells (PBPCs). This agent works synergistically with other hematopoietic growth factors. rhSCF may promote bone marrow recovery after myeloablative therapies and procedures. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1410" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1410" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000041929

altLabel

steel factor

c-kit ligand

Recombinant Stem Cell factor

mast-cell growth factor

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000038008

http://purl.bioontology.org/ontology/PDQ/CDR0000042109

cui

C1526982

Date last modified

2017-12-11

definition

A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant human stem cell factor (rhSCF) binds to the receptor tyrosine kinase c-kit, which may stimulate the growth of peripheral blood progenitor cells (PBPCs). This agent works synergistically with other hematopoietic growth factors. rhSCF may promote bone marrow recovery after myeloablative therapies and procedures. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1410" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1410" NCI Thesaurus)

Legacy PDQ ID

5151

NCI ID

C1410

notation

CDR0000041929

ORIG STY

Drug/agent

prefLabel

recombinant human stem cell factor

tui

T116

T123

T121

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