Preferred Name |
recombinant human stem cell factor |
|
Synonyms |
steel factor |
|
Definitions |
A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant human stem cell factor (rhSCF) binds to the receptor tyrosine kinase c-kit, which may stimulate the growth of peripheral blood progenitor cells (PBPCs). This agent works synergistically with other hematopoietic growth factors. rhSCF may promote bone marrow recovery after myeloablative therapies and procedures. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1410" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1410" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000041929 |
|
altLabel |
steel factor c-kit ligand Recombinant Stem Cell factor mast-cell growth factor |
|
Component of | ||
cui |
C1526982 |
|
Date last modified |
2017-12-11 |
|
definition |
A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant human stem cell factor (rhSCF) binds to the receptor tyrosine kinase c-kit, which may stimulate the growth of peripheral blood progenitor cells (PBPCs). This agent works synergistically with other hematopoietic growth factors. rhSCF may promote bone marrow recovery after myeloablative therapies and procedures. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1410" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1410" NCI Thesaurus) |
|
Legacy PDQ ID |
5151 |
|
NCI ID |
C1410 |
|
notation |
CDR0000041929 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
recombinant human stem cell factor |
|
tui |
T116 T123 T121 |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.obolibrary.org/obo/NCIT_C1410 | BERO | LOOM | |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1410 | NCIT | LOOM |