loading...| Preferred Name |
morphine sulfate |
|
| Synonyms |
MS Contin |
|
| Definitions |
The sulfate salt of morphine, an opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. Morphine binds to and activates specific opiate receptors (delta, mu and kappa), each of which are involved in controlling different brain functions. In the central nervous and gastrointestinal systems, this agent has widespread effects including analgesia, anxiolysis, euphoria, sedation, respiratory depression, and gastrointestinal system smooth muscle contraction. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C669" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C669" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000041804 |
|
| altLabel |
MS Contin Infumorph MSir MORPH Kadian Oramorph SR Avinza Roxanol Oramorph Statex SR |
|
| CAS Registry |
64-31-3 6211-15-0 |
|
| Component of | ||
| cui |
C0591917 C0700655 C0700788 C0026549 C1170078 C0919266 C0700790 C0700785 C0700786 C0066814 C0700789 |
|
| Date last modified |
2017-12-11 |
|
| definition |
The sulfate salt of morphine, an opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. Morphine binds to and activates specific opiate receptors (delta, mu and kappa), each of which are involved in controlling different brain functions. In the central nervous and gastrointestinal systems, this agent has widespread effects including analgesia, anxiolysis, euphoria, sedation, respiratory depression, and gastrointestinal system smooth muscle contraction. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C669" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C669" NCI Thesaurus) |
|
| Legacy PDQ ID |
499 |
|
| LT |
TRD |
|
| NCI ID |
C669 |
|
| notation |
CDR0000041804 |
|
| NSC Code |
11441 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
morphine sulfate |
|
| tui |
T109 T121 |