Physician Data Query

Last uploaded: April 29, 2019
Preferred Name

chlorhexidine

Definitions

A biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram positive bacteria are more negatively charged, they are more sensitive to this agent. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41544&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41544&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C364" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000041544

CAS Registry

55-56-1

cui

C0008196

definition

A biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram positive bacteria are more negatively charged, they are more sensitive to this agent. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41544&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41544&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C364" NCI Thesaurus)

Legacy PDQ ID

4704

NCI ID

C364

notation

CDR0000041544

ORIG STY

Drug/agent

prefLabel

chlorhexidine

tui

T109

T121

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http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.078.370.141.100 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Chlorhexidine GALEN LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000006835 NDFRT CUI
http://purl.bioontology.org/ontology/SNMI/C-90250 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-90250 SNMI LOOM
http://purl.jp/bio/4/id/200906045186180011 IOBC LOOM
http://purl.jp/bio/4/id/200906045186180011 IOBC LOOM
http://purl.jp/bio/4/id/200906045186180011 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147765 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000147765 NDFRT LOOM
http://purl.bioontology.org/ontology/MESH/D002710 MESH CUI
http://purl.bioontology.org/ontology/MESH/D002710 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002710 RH-MESH LOOM
http://data.bnf.fr/ark:/12148/cb12266566s FAST-TOPICAL LOOM
http://purl.bioontology.org/ontology/UATC/S01AX09 ATC CUI
http://purl.bioontology.org/ontology/UATC/S01AX09 ATC LOOM
http://purl.bioontology.org/ontology/UATC/S03AA04 ATC CUI
http://purl.bioontology.org/ontology/UATC/S03AA04 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4019673 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4019673 VANDF LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_3614 EFO LOOM
http://purl.bioontology.org/ontology/UATC/S02AA09 ATC CUI
http://purl.bioontology.org/ontology/UATC/S02AA09 ATC LOOM
http://purl.bioontology.org/ontology/RCD/x001v RCD CUI
http://purl.bioontology.org/ontology/RCD/x001v RCD LOOM
http://purl.bioontology.org/ontology/UATC/D09AA12 ATC CUI
http://purl.bioontology.org/ontology/UATC/D09AA12 ATC LOOM
http://purl.bioontology.org/ontology/NDDF/003674 NDDF CUI
http://purl.bioontology.org/ontology/NDDF/003674 NDDF LOOM
http://purl.bioontology.org/ontology/LNC/LP128648-5 LOINC CUI
http://purl.bioontology.org/ontology/LNC/LP128648-5 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/2358 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/2358 RXNORM LOOM
http://purl.bioontology.org/ontology/UATC/R02AA05 ATC CUI
http://purl.bioontology.org/ontology/UATC/R02AA05 ATC LOOM
http://purl.bioontology.org/ontology/UATC/B05CA02 ATC CUI
http://purl.bioontology.org/ontology/UATC/B05CA02 ATC LOOM
http://stirdf.jst.go.jp/id/200907087158651090 IOBC LOOM
http://stirdf.jst.go.jp/id/200907087158651090 IOBC LOOM
http://stirdf.jst.go.jp/id/200907087158651090 IOBC LOOM
http://purl.bioontology.org/ontology/UATC/D08AC02 ATC CUI
http://purl.bioontology.org/ontology/UATC/D08AC02 ATC LOOM
http://purl.bioontology.org/ontology/UATC/A01AB03 ATC CUI
http://purl.bioontology.org/ontology/UATC/A01AB03 ATC LOOM
http://purl.bioontology.org/ontology/CSP/1357-0106 CRISP CUI
http://purl.bioontology.org/ontology/CSP/1357-0106 CRISP LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/96316004 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/373568007 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/373568007 SNOMEDCT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C364 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C364 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C364 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C364 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C364 NCIT LOOM