loading...| Preferred Name |
glycine |
|
| Synonyms |
Gly |
|
| Definitions |
A non-essential, non-polar, non-optical, glucogenic amino acid. Glycine, an inhibitory neurotransmitter in the CNS, triggers chloride ion influx via ionotropic receptors, thereby creating an inhibitory post-synaptic potential. In contrast, this agent also acts as a co-agonist, along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is an important component and precursor for many macromolecules in the cells. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C524" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C524" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000041347 |
|
| altLabel |
Gly aminoethanoic acid |
|
| CAS Registry |
56-40-6 |
|
| cui |
C0017890 |
|
| Date last modified |
2008-10-15 |
|
| definition |
A non-essential, non-polar, non-optical, glucogenic amino acid. Glycine, an inhibitory neurotransmitter in the CNS, triggers chloride ion influx via ionotropic receptors, thereby creating an inhibitory post-synaptic potential. In contrast, this agent also acts as a co-agonist, along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is an important component and precursor for many macromolecules in the cells. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C524" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C524" NCI Thesaurus) |
|
| Legacy PDQ ID |
4419 |
|
| NCI ID |
C524 |
|
| notation |
CDR0000041347 |
|
| NSC Code |
25936 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
glycine |
|
| tui |
T116 T123 T121 |