loading...| Preferred Name |
beta carotene |
|
| Synonyms |
Solatene |
|
| Definitions |
A naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA. This agent also induces cell differentiation and apoptosis of some tumor cell types, particularly in early stages of tumorigenesis, and enhances immune system activity by stimulating the release of natural killer cells, lymphocytes, and monocytes. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1016" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1016" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000040992 |
|
| altLabel |
Solatene Lumitene |
|
| CAS Registry |
7235-40-7 |
|
| Component of |
http://purl.bioontology.org/ontology/PDQ/CDR0000445226 |
|
| cui |
C0728799 C1831594 C0053396 |
|
| Date last modified |
2006-12-06 |
|
| definition |
A naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA. This agent also induces cell differentiation and apoptosis of some tumor cell types, particularly in early stages of tumorigenesis, and enhances immune system activity by stimulating the release of natural killer cells, lymphocytes, and monocytes. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1016" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1016" NCI Thesaurus) |
|
| Legacy PDQ ID |
4030 |
|
| LT |
TRD |
|
| NCI ID |
C1016 |
|
| notation |
CDR0000040992 |
|
| NSC Code |
62794 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
beta carotene |
|
| tui |
T109 T127 T121 |