Preferred Name |
ciprofloxacin |
|
Synonyms |
CPFX |
|
Definitions |
A synthetic broad spectrum fluoroquinolone antibiotic. Ciprofloxacin binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA replication. This agent is more active against Gram-negative bacteria than Gram-positive bacteria. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C375" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C375" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000040784 |
|
altLabel |
CPFX Cipro 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid |
|
CAS Registry |
85721-33-1 |
|
Component of |
http://purl.bioontology.org/ontology/PDQ/CDR0000429575 http://purl.bioontology.org/ontology/PDQ/CDR0000042812 http://purl.bioontology.org/ontology/PDQ/CDR0000041923 http://purl.bioontology.org/ontology/PDQ/CDR0000041921 http://purl.bioontology.org/ontology/PDQ/CDR0000306457 http://purl.bioontology.org/ontology/PDQ/CDR0000041870 http://purl.bioontology.org/ontology/PDQ/CDR0000042012 http://purl.bioontology.org/ontology/PDQ/CDR0000042011 |
|
cui |
C0008809 C0701042 |
|
Date last modified |
2006-07-31 |
|
definition |
A synthetic broad spectrum fluoroquinolone antibiotic. Ciprofloxacin binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA replication. This agent is more active against Gram-negative bacteria than Gram-positive bacteria. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C375" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C375" NCI Thesaurus) |
|
Legacy PDQ ID |
3748 |
|
LT |
TRD |
|
NCI ID |
C375 |
|
notation |
CDR0000040784 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
ciprofloxacin |
|
tui |
T109 T121 |