loading...| Preferred Name |
ondansetron |
|
| Synonyms |
Zofran |
|
| Definitions |
A carbazole derivative with antiemetic activity. As a selective serotonin receptor antagonist, ondansetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1119" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1119" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000040693 |
|
| altLabel |
Zofran |
|
| CAS Registry |
16002-70-1 99614-02-5 |
|
| Component of | ||
| cui |
C0206046 C0061851 |
|
| Date last modified |
2017-11-21 |
|
| definition |
A carbazole derivative with antiemetic activity. As a selective serotonin receptor antagonist, ondansetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1119" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1119" NCI Thesaurus) |
|
| Legacy PDQ ID |
3630 |
|
| LT |
TRD |
|
| NCI ID |
C1119 |
|
| notation |
CDR0000040693 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
ondansetron |
|
| tui |
T109 T121 |