Physician Data Query

Last uploaded: April 29, 2019
Preferred Name

pentamidine

Synonyms

Aerosolized Pentamadine

Definitions

A synthetic derivative of amidine with antiprotozoal and antifungal activities. Although the precise mode of action of pentamidine is unclear, it appears to interact directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40324&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40324&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C731" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000040324

altLabel

Aerosolized Pentamadine

CAS Registry

100-33-4

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000041173

http://purl.bioontology.org/ontology/PDQ/CDR0000039393

cui

C0030863

Date last modified

2006-12-27

definition

A synthetic derivative of amidine with antiprotozoal and antifungal activities. Although the precise mode of action of pentamidine is unclear, it appears to interact directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40324&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40324&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C731" NCI Thesaurus)

Legacy PDQ ID

3166

NCI ID

C731

notation

CDR0000040324

NSC Code

9921

ORIG STY

Drug/agent

prefLabel

pentamidine

tui

T109

T121

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.078.100.700 RH-MESH LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005537 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005537 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005537 DMTO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147966 ODAE LOOM
http://purl.bioontology.org/ontology/MESH/D010419 MESH CUI
http://purl.bioontology.org/ontology/MESH/D010419 MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C731 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C731 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C731 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C731 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C731 NCIT LOOM
http://stirdf.jst.go.jp/id/200907024698542981 IOBC LOOM
http://stirdf.jst.go.jp/id/200907024698542981 IOBC LOOM
http://stirdf.jst.go.jp/id/200907024698542981 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372699006 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/372699006 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005544 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005544 DMTO LOOM
http://purl.jp/bio/4/id/200906001301045800 IOBC LOOM
http://purl.jp/bio/4/id/200906001301045800 IOBC LOOM
http://purl.jp/bio/4/id/200906001301045800 IOBC LOOM
http://purl.bioontology.org/ontology/RCD/x01JH RCD CUI
http://purl.bioontology.org/ontology/RCD/x01JH RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010419 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/7994 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/7994 RXNORM LOOM
http://purl.bioontology.org/ontology/CSP/0114-0900 CRISP CUI
http://purl.bioontology.org/ontology/CSP/0114-0900 CRISP LOOM
http://purl.bioontology.org/ontology/SNMI/C-52050 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-52050 SNMI LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/31692006 SNOMEDCT CUI
http://purl.obolibrary.org/obo/CHEBI_45081 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_45081 EFO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000005709 NDFRT CUI
http://purl.bioontology.org/ontology/VANDF/4019881 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4019881 VANDF LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147966 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000147966 NDFRT LOOM
http://www.drugbank.ca/drugs/DB00738 FTC LOOM