loading...| Preferred Name |
naproxen |
|
| Synonyms |
RS-3540 |
|
| Definitions |
A propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of naproxen. Naproxen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C680" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C680" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000040222 |
|
| altLabel |
RS-3540 d-2-(6-Methoxy-2-naphthyl)propionic Acid 6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid Naprosyn |
|
| CAS Registry |
22204-53-1 |
|
| cui |
C0027396 C1764836 C0700017 |
|
| definition |
A propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of naproxen. Naproxen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C680" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C680" NCI Thesaurus) |
|
| Legacy PDQ ID |
3032 |
|
| LT |
TRD |
|
| NCI ID |
C680 |
|
| notation |
CDR0000040222 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
naproxen |
|
| tui |
T109 T121 |