loading...| Preferred Name |
hydrazine sulfate |
|
| Synonyms |
Sehydrin |
|
| Definitions |
The synthetic sulfate salt of hydrazine, a derivative of ammonia. Hydrazine inhibits the enzyme phosphoenol pyruvate carboxykinase, thereby blocking gluconeogenesis. This agent has been reported to decrease the excessive energy needs and cachexia of cancer patients. Classified as a likely human carcinogen, hydrazine sulfate is also a weak inhibitor of mono-amine oxidase (MAO). Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1129" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1129" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000040141 |
|
| altLabel |
Sehydrin |
|
| CAS Registry |
10034-93-2 |
|
| Component of | ||
| cui |
C1512522 C0063067 |
|
| Date last modified |
2006-12-20 |
|
| definition |
The synthetic sulfate salt of hydrazine, a derivative of ammonia. Hydrazine inhibits the enzyme phosphoenol pyruvate carboxykinase, thereby blocking gluconeogenesis. This agent has been reported to decrease the excessive energy needs and cachexia of cancer patients. Classified as a likely human carcinogen, hydrazine sulfate is also a weak inhibitor of mono-amine oxidase (MAO). Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C1129" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1129" NCI Thesaurus) |
|
| IND Code |
33233 |
|
| Legacy PDQ ID |
2906 |
|
| LT |
TRD |
|
| NCI ID |
C1129 |
|
| notation |
CDR0000040141 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
hydrazine sulfate |
|
| tui |
T197 T109 T121 |