Physician Data Query

Last uploaded: August 27, 2019
Preferred Name

dacarbazine

Synonyms

Deticene

Definitions

A triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C411" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C411" NCI Thesaurus)

ID

http://purl.bioontology.org/ontology/PDQ/CDR0000039768

altLabel

Deticene

Dakarbazin

dimethyl-triazeno-imidazole carboxamide

Biocarbazine

Dacarbazina

Dimethyl Triazeno Imidazol Carboxamide

Imidazole Carboxamide Dimethyltriazeno

Asercit

Dimethyl Triazeno Imidazole Carboxamide

5(or 4)-(dimethyltriazeno)imidazole-4(or 5)-carboxamide

1H-imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-

Dacarbazina Almirall

Imidazole Carboxamide

Fauldetic

WR-139007

DTIC

Detimedac

5-(3-3-dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide

Dacarbazine - DTIC

Dacatic

DIC

5-(dimethyltriazeno)imidazole-4-carboxamide

Dimethyl (triazeno) imidazolecarboxamide

CAS Registry

4342-03-4

Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000040417

http://purl.bioontology.org/ontology/PDQ/CDR0000041140

http://purl.bioontology.org/ontology/PDQ/CDR0000038841

http://purl.bioontology.org/ontology/PDQ/CDR0000038434

http://purl.bioontology.org/ontology/PDQ/CDR0000039686

http://purl.bioontology.org/ontology/PDQ/CDR0000257909

http://purl.bioontology.org/ontology/PDQ/CDR0000043252

http://purl.bioontology.org/ontology/PDQ/CDR0000039775

http://purl.bioontology.org/ontology/PDQ/CDR0000041277

http://purl.bioontology.org/ontology/PDQ/CDR0000038846

http://purl.bioontology.org/ontology/PDQ/CDR0000435983

http://purl.bioontology.org/ontology/PDQ/CDR0000038276

http://purl.bioontology.org/ontology/PDQ/CDR0000363628

http://purl.bioontology.org/ontology/PDQ/CDR0000040471

http://purl.bioontology.org/ontology/PDQ/CDR0000040946

http://purl.bioontology.org/ontology/PDQ/CDR0000042279

http://purl.bioontology.org/ontology/PDQ/CDR0000352012

http://purl.bioontology.org/ontology/PDQ/CDR0000042126

http://purl.bioontology.org/ontology/PDQ/CDR0000042047

http://purl.bioontology.org/ontology/PDQ/CDR0000041916

http://purl.bioontology.org/ontology/PDQ/CDR0000041037

http://purl.bioontology.org/ontology/PDQ/CDR0000042269

http://purl.bioontology.org/ontology/PDQ/CDR0000039416

http://purl.bioontology.org/ontology/PDQ/CDR0000042280

http://purl.bioontology.org/ontology/PDQ/CDR0000257908

http://purl.bioontology.org/ontology/PDQ/CDR0000039693

http://purl.bioontology.org/ontology/PDQ/CDR0000042552

http://purl.bioontology.org/ontology/PDQ/CDR0000041365

http://purl.bioontology.org/ontology/PDQ/CDR0000041036

http://purl.bioontology.org/ontology/PDQ/CDR0000353183

http://purl.bioontology.org/ontology/PDQ/CDR0000038890

http://purl.bioontology.org/ontology/PDQ/CDR0000042463

http://purl.bioontology.org/ontology/PDQ/CDR0000039351

http://purl.bioontology.org/ontology/PDQ/CDR0000041377

http://purl.bioontology.org/ontology/PDQ/CDR0000039432

http://purl.bioontology.org/ontology/PDQ/CDR0000039390

http://purl.bioontology.org/ontology/PDQ/CDR0000415314

http://purl.bioontology.org/ontology/PDQ/CDR0000041364

http://purl.bioontology.org/ontology/PDQ/CDR0000042053

http://purl.bioontology.org/ontology/PDQ/CDR0000039400

http://purl.bioontology.org/ontology/PDQ/CDR0000040947

http://purl.bioontology.org/ontology/PDQ/CDR0000042268

http://purl.bioontology.org/ontology/PDQ/CDR0000041332

http://purl.bioontology.org/ontology/PDQ/CDR0000040354

http://purl.bioontology.org/ontology/PDQ/CDR0000039389

http://purl.bioontology.org/ontology/PDQ/CDR0000039976

http://purl.bioontology.org/ontology/PDQ/CDR0000042013

http://purl.bioontology.org/ontology/PDQ/CDR0000038605

http://purl.bioontology.org/ontology/PDQ/CDR0000041941

http://purl.bioontology.org/ontology/PDQ/CDR0000039701

http://purl.bioontology.org/ontology/PDQ/CDR0000041141

http://purl.bioontology.org/ontology/PDQ/CDR0000042139

http://purl.bioontology.org/ontology/PDQ/CDR0000042445

http://purl.bioontology.org/ontology/PDQ/CDR0000039372

http://purl.bioontology.org/ontology/PDQ/CDR0000361549

http://purl.bioontology.org/ontology/PDQ/CDR0000442900

http://purl.bioontology.org/ontology/PDQ/CDR0000041376

http://purl.bioontology.org/ontology/PDQ/CDR0000038553

http://purl.bioontology.org/ontology/PDQ/CDR0000039120

http://purl.bioontology.org/ontology/PDQ/CDR0000039452

http://purl.bioontology.org/ontology/PDQ/CDR0000040936

http://purl.bioontology.org/ontology/PDQ/CDR0000040472

http://purl.bioontology.org/ontology/PDQ/CDR0000040314

http://purl.bioontology.org/ontology/PDQ/CDR0000039604

http://purl.bioontology.org/ontology/PDQ/CDR0000042208

http://purl.bioontology.org/ontology/PDQ/CDR0000041366

http://purl.bioontology.org/ontology/PDQ/CDR0000039119

cui

C1511709

C1521710

C0010927

C1521711

C0728896

C0728898

C1511711

C1511712

C0392206

C1511710

Date last modified

2018-01-10

definition

A triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C411" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C411" NCI Thesaurus)

IND Code

3188

Legacy PDQ ID

243

LT

TRD

NCI ID

C411

notation

CDR0000039768

NSC Code

45388

ORIG STY

Drug/agent

prefLabel

dacarbazine

tui

T109

T121

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http://phenomebrowser.net/ontologies/mesh/mesh.owl#D003606 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.129.308.240 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4018386 VANDF CUI
http://purl.bioontology.org/ontology/VANDF/4018386 VANDF LOOM
http://purl.bioontology.org/ontology/SCTSPA/387441003 SCTSPA CUI
http://purl.bioontology.org/ontology/SNOMEDCT/77750008 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SCTSPA/77750008 SCTSPA CUI
http://purl.obolibrary.org/obo/CHEBI_4305 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 NIFSTD LOOM
http://purl.bioontology.org/ontology/MSHFRE/D003606 MSHFRE CUI
http://purl.bioontology.org/ontology/SNMI/C-78090 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-78090 SNMI CUI
http://purl.bioontology.org/ontology/SNMI/C-78090 SNMI LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3597 OCHV LOOM
http://purl.jp/bio/4/id/200906004842005622 IOBC LOOM
http://purl.bioontology.org/ontology/CSP/1548-5964 CRISP CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387441003 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387441003 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387441003 SNOMEDCT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C411 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C411 NCIT LOOM
http://purl.bioontology.org/ontology/MESH/D003606 MESH CUI
http://purl.bioontology.org/ontology/MESH/D003606 MESH CUI
http://purl.bioontology.org/ontology/MESH/D003606 MESH CUI
http://purl.bioontology.org/ontology/MESH/D003606 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.925.200 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146713 NDFRT CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146713 NDFRT LOOM
http://stirdf.jst.go.jp/id/200907031160358150 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/002671 NDDF CUI
http://purl.bioontology.org/ontology/NDDF/002671 NDDF LOOM
http://purl.bioontology.org/ontology/RCD/h54.. RCD CUI
http://purl.bioontology.org/ontology/RCD/h54.. RCD CUI
http://purl.bioontology.org/ontology/RCD/h54.. RCD LOOM
http://purl.bioontology.org/ontology/RCD/x02ab RCD CUI
http://purl.bioontology.org/ontology/UATC/L01AX04 ATC CUI
http://purl.bioontology.org/ontology/UATC/L01AX04 ATC LOOM
http://purl.bioontology.org/ontology/RXNORM/3098 RXNORM CUI
http://purl.bioontology.org/ontology/RXNORM/3098 RXNORM LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000006842 NDFRT CUI
http://www.drugbank.ca/drugs/DB00851 FTC LOOM
http://www.co-ode.org/ontologies/galen#Dacarbazine GALEN LOOM
http://purl.bioontology.org/ontology/CSP/1548-5525 CRISP CUI
http://purl.bioontology.org/ontology/CSP/1548-5525 CRISP LOOM